Answered: A crossover trial is a type of…

Name: A crossover trial is a type of experiment used to compare two drugs. S
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Description: A crossover trial is a type of experiment used to compare two drugs. Subjects take one drug for a period of time, then switch to the other. The responses of the subjects are compared using matched-pair-methods. in an experiment to compare two pain re

MATLAB: An Introduction with Applications

6th Edition

ISBN:9781119256830

Author:Amos Gilat

Publisher:Amos Gilat

Chapter1: Starting With Matlab

Section: Chapter Questions

Problem 1P

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A crossover trial is a type of experiment used to compare two drugs. Subjects take one drug for a period of time, then switch to the other. The responses of the subjects are compared using matched-pair-methods. in an experiment to compare two pain relievers, seven subjects took one pain reliever for two weeks, then switched to the other. They rated their pain level from 1 to 10, with larger numbers representing higher levels of pain. The results were:

Drug A 6 3 4 5 7 1 4

Drug B 5 1 5 5 5 2 2

can you conclude that the mean pain level is less with drug B?

a. State the null and alternate hypothesis

b. Compute the test statistic.

c. State a conclusion. Use a= 0.05 level of significance.

Definition Definition Measure of central tendency that is the average of a given data set. The mean value is evaluated as the quotient of the sum of all observations by the sample size. The mean, in contrast to a median, is affected by extreme values. Very large or very small values can distract the mean from the center of the data. Arithmetic mean: The most common type of mean is the arithmetic mean. It is evaluated using the formula: μ = 1 N ∑ i = 1 N x i Other types of means are the geometric mean, logarithmic mean, and harmonic mean. Geometric mean: The nth root of the product of n observations from a data set is defined as the geometric mean of the set: G = x 1 x 2 ... x n n Logarithmic mean: The difference of the natural logarithms of the two numbers, divided by the difference between the numbers is the logarithmic mean of the two numbers. The logarithmic mean is used particularly in heat transfer and mass transfer. ln x 2 − ln x 1 x 2 − x 1 Harmonic mean: The inverse of the arithmetic mean of the inverses of all the numbers in a data set is the harmonic mean of the data. 1 1 x 1 + 1 x 2 + ...

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