A clinical trial is being conducted in order to determine the efficacy of a new drug that will be used to treat Crohn’s disease. The efficacy of the medication will not only be determined by the physical improvement of symptoms but will also be determined by using a blood test to examine the concentration C-reactive protein (an inflammatory marker) in an individual’s blood. If the researcher wants a margin of error for the level of C-reactive protein to be less than or equal to 2.9 mg/dL and the standard deviation for C-reactive protein concentrations among Crohn’s disease patients was previously documented at 10.1 mg/dL, how many patients should be recruited for each group of individuals in the study, assuming a 95% confidence interval will be used to quantify the mean differences between the control group and the treatment group? Group of answer choices n for the treatment group = 12 and n for the control group = 12 n for the treatment group = 14 and n for the control group = 14 n for the treatment group = 47 and n for the control group = 47 n for the treatment group = 94 and n for the control group = 94

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A clinical trial is being conducted in order to determine the efficacy of a new drug that will be used to treat Crohn’s disease. The efficacy of the medication will not only be determined by the physical improvement of symptoms but will also be determined by using a blood test to examine the concentration C-reactive protein (an inflammatory marker) in an individual’s blood. If the researcher wants a margin of error for the level of C-reactive protein to be less than or equal to 2.9 mg/dL and the standard deviation for C-reactive protein concentrations among Crohn’s disease patients was previously documented at 10.1 mg/dL, how many patients should be recruited for each group of individuals in the study, assuming a 95% confidence interval will be used to quantify the mean differences between the control group and the treatment group?
Group of answer choices
n
for the treatment group = 12 and n for the control group = 12
n
for the treatment group = 14 and n for the control group = 14
n
for the treatment group = 47 and n for the control group = 47
n
for the treatment group = 94 and n for the control group = 94
 
Expert Solution
Step 1

Given Information:

Margin of error E = 2.9

Standard deviation is 10.1 (same for each group).

Assume that the sample size of control and treatment group are the same.

Confidence level is 95%

Significance level α=1-0.95=0.05

 

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