(a) Calculate the aggregated odds ratio for the association between paternal age and autism. (b) Calculate the Mantel-Haenszel odds ratio for the association between paternal age and autism, adjusting for the effect of gender. (c) Interpret your results

MATLAB: An Introduction with Applications
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A cohort study investigated whether there was an association between
paternal age and the risk of autism. An excerpt of the data is given in
Tables 4 and 5, stratified by gender.
Table 4: Females
Paternal Age Child with Autism Child without Autism Total
3
28553
28556
10
32139
32149
15-29
30-39
Table 5: Males
Paternal Age Child with Autism Child without Autism Total
31
32101
32132
52
35072
35124
15-29
30-39
(a) Calculate the aggregated odds ratio for the association between
paternal age and autism.
(b) Calculate the Mantel-Haenszel odds ratio for the association
between paternal age and autism, adjusting for the effect of
gender.
(c) Interpret your results
Transcribed Image Text:A cohort study investigated whether there was an association between paternal age and the risk of autism. An excerpt of the data is given in Tables 4 and 5, stratified by gender. Table 4: Females Paternal Age Child with Autism Child without Autism Total 3 28553 28556 10 32139 32149 15-29 30-39 Table 5: Males Paternal Age Child with Autism Child without Autism Total 31 32101 32132 52 35072 35124 15-29 30-39 (a) Calculate the aggregated odds ratio for the association between paternal age and autism. (b) Calculate the Mantel-Haenszel odds ratio for the association between paternal age and autism, adjusting for the effect of gender. (c) Interpret your results
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