A boy with Klinefelter syndrome (47,XXY) is born to a motherwho is phenotypically normal and a father who has the X-linkedskin condition called anhidrotic ectodermal dysplasia. The mother’sskin is completely normal with no signs of the skin abnormality.In contrast, her son has patches of normal skin and patchesof abnormal skin. Question: Which parent contributed the abnormal gamete?

Q: Trisomy 21, or Down syndrome, occurs when there is a normal diploid chromosomal complement but one…

A: Down's syndrome occurs due to an error at the time of gamete formation. As a result the gametes may…

Q: In humans, as well as in many other animals and some plants, the sex of the individual is determined…

A: Haemophilia is an inherited bleeding disorder where blood doesn't clot properly. It is caused when…

Q: How can epistasis explain incomplete penetrance?

A: Penetrance in genetic terms refers to the ratio of individuals that carry a specific allele of a…

Q: In this pedigree, affected individuals have a disease causing the inability to walk forward, called…

A: Genes are the hereditary unit of an organism. The genes have DNA (deoxyribonucleic acid) which code…

Q: What is the probability that a carrier wom en will transmit an abnomal X-linked gene to her son?…

A: Pedigree analysis is the pattern of analyzing the inheritance of disease/disorder from one…

Q: Glucose-6-phosphate dehydrogenase deficiency (G6PD) is inherited as an X-linked recessive gene in…

A: Glucose 6-phosphate dehydrogenase deficiency is inherited as an X-linked recessive gene. Woman has…

Q: As Ashley cares for her son, she notices some problems in his development. During one of the baby’s…

A: Duchenne muscular dystrophy (DMD) is a genetic disorder characterized by progressive muscle…

Q: Campomelic dysplasia (CMD1) is a congenital humansyndrome featuring malformation of bone and…

A: Campomelic dysplasia is a rare genetic disorder characterized by bowing of the long bones and many…

Q: X-linked lissencephaly is an X-link dominant trait pertaining to a brain disorder. It superficially…

A: Given information Lissencephaly is an X-linked dominant trait Mr. Panganiban is affected by the…

Q: Hemophilia A is transmitted by an X-linked recessive gene.With an affected father, what is the…

A: Answer: Introduction: In X-linked recessive disorders, an affected father has a mutation in a gene…

Q: What is the percentage chance that individual V.2 , will have inherited the X-linked recessive…

A: X-linked recessive diseases are the diseases which  are passsed from the female carrier to males. So…

Q: Give the phenotypic effects and chromosomal aberrations of the following syndromes/disorders: Down…

A: DOWN SYNDROME. Down syndrome is the most common chromosomal disorder due to the autosomal trisomy of…

Q: A variety of abnormalities in the numbers of sex chromosomes exist because of nondisjunction during…

A:

Q: Mr. and Mrs. Smith, both 40 years of age, are healthy with no knowngenetic conditions. Their newborn…

A: Down syndrome is defined as the condition in which an individual contains an extra chromosome. In…

Q: Mrs. Dee (40 years old) and her husband have an amniocentesis for advanced maternal age. They…

A: The amniocentesis is performed for the genetical analysis of the fetus. It helps in the early…

Q: Please draw it out so I understand how it's suppose to be drawn

A: I hope this was helpful If any doubts please ask for clarificationPlease give helpful rating if you…

Q: Why is the development of individuals with Klinefelter's and Turner's syndromes relatively normal,…

A: This syndrome occur due to presence of an additional copy of X chromosomes resulting into karyotype…

Q: inheritance

A: Pedigree analysis is a crucial method used in genetics to understand the inheritance patterns of…

Q: Table 8.1 shows that Turner syndrome occurs when an individual inherits one X chromosome but lacks a…

A: Chromosomal deletion syndrome occurs when whole or part of chromosomes are missing. Turner Syndrome…

Q: Explain why genetic disorders caused by recessive alleles of X-linked genes appear more frequently…

A: In humans and other mammals, biological sex is determined by a pair of sex chromosomes: XY in males…

Q: When examining a human pedigree, what features do you look forto distinguish between X-linked…

A: Genetic disorders are of different types depending on the location of the infected genes and the…

Q: A human female heterozygous for X-linked trait causing red-green color blindness marries a red-green…

A: Red Green Colour Blindness:  Red-green color blindness is a type of color vision deficiency where…

Q: Drosophila females of wild-type appearance but heterozygous for three autosomal genes are mated with…

A: Let us represent the alleles responsible for wildtype eyes, wildtype bodies, and wildtype thoraxes…

Q: A family has an X-linked dominant form of congenital generalizedhypertrichosis (excessive…

A: Genes are the functional unit of DNA. It contains information that is transferred from one…

Q: Wild-type giraffes have long necks. Below is a pedigree of a family of giraffes that has a history…

A: The Pedigree shown here is based on autosomal recessive inheritance pattern which means that the…

Q: Constructing and Using a Pedigree Duchenne's muscular dystrophy (DMD) is a well known, lethal…

A: A pedigree chart is a graphic that depicts the incidence and emergence of phenotypes of a gene or…

Q: A 31 year old woman consults her physicain because she is concerned about developing breast cancer.…

A: Abnormal and uncontrolled growth and proliferation of cells with a capacity to invade other healthy…

Q: The mutant FMR-1 allele that causes fragile X syndrome is considered to be X-linked dominant…

A: Fragile X syndrome is a genetic disorder. It causes various developmental disorders that include…

Q: Wilma and Wally have one male child who has been diagnosed withDuchenne muscular dystrophy, an…

A: Duchenne muscular dystrophy is a medical condition of muscular dystrophy which is caused by DMD gene…

Q: Amelogenesis imperfecta (AI) is a disorder of faulty tooth enamel formation. It is inherited in an…

A: Genes are the unit of inheritance that transfers traits from one generation to another. Genes coding…

Q: A women is heterozygous, Aa, for classic albinism and this gene maps to chromosome 11, and is a…

A: Oogenesis is the process of formation of female gametes called ovum or egg. The development of eggs…

Q: Mutations of the CFTR gene causes ( Cerebral Plasy or Cystic Fibrosis or Craniofacial timbrosis or…

A: Mutations of the CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) gene primarily cause…

Q: Charles has achondroplasia dwarfism (autosomal dominant) but his wife is normal. What is the…

A:

Q: Q1: How many male and how many female descendants (individuals that did not join the family by…

A: The traits that are present or absent in a family over generations are shown in a pedigree.I…

Q: What is incomplete penetrance and what causes it?

A: Introduction  Any gene have two alleles pairs viz. Dominant or Recessive. The allele which gets…

Q: Kelly and Sam are both unaffected carriers for two autosomal recessive disorders, PKU (chromosome…

A: Sir Gregor Mendel was a priest and a teacher who did the famous hybridization experiment on garden…

Q: Amelogenesis imperfecta (AI) is a disorder of faulty tooth enamel formation. It is inherited in an…

A: Amelogenesis imperfecta (AI) is a disorder of faulty tooth enamel formation. It is inherited in an…

Q: What is Trisomy test?

A: The chromosomes are the thread like structure that contains hereditary information in the form of…

Q: Can a son be a carrier for an X-linked trait? Explain.

A: The genetic makeup of an offspring is determined by the genetic makeup of both parents; that is, the…

Q: Could a woman who expresses the x-linked color-blind trait have a son with normal vision?

A: BASIC INFORMATION  COLOR BLINDNESS  it is an X - linked recessive trait  in this the eye is not…

Q: You have spent two decades studying a muscular dystrophy disorder. All previous pedigree data…

A: X linked disease is a type of sex linked disease in which the mutation is present in X chromosome.…

Q: Why does a single X chromosome cause infertility and other abnormalities in Turner Syndrome…

A: Turner syndrome (TS) is a genetic disorder that mostly affects females. The clinical features of…

Q: What are chromosomal Defects. List and Explain any 5 of them.

A: Almost every cell in our body contains 23 pairs of chromosomes, for a total of 46 chromosomes. Half…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.