A batch of codeine phosphate powder was analysed according to the BP (1999) method described below. "Dissolve 0.350 g in a mixture of 10 mL anhydrous acetic acid and 20 mL of 1,4-dioxan R. Titrate with 0.1 M perchloric acid (MM 100.46 g/mol) using 0.05 mL of crystal violet solution R as indicator." The following results were obtained: Weight of powder taken for analysis 0.3495 g 8.53 mL Volume of 0.1 M HCIO, required to neutralise the base Concentration of HCIO4 = = 0.09923 M Calculate the percentage purity of codeine phosphate. Explain your reasoning clearly

A batch of codeine phosphate powder was analysed according to the BP (1999) method described below. "Dissolve 0.350 g in a mixture of 10 mL anhydrous acetic acid and 20 mL of 1,4-dioxan R. Titrate with 0.1 M perchloric acid (MM 100.46 g/mol) using 0.05 mL of crystal violet solution R as indicator." The following results were obtained: Weight of powder taken for analysis 0.3495 g 8.53 mL Volume of 0.1 M HCIO, required to neutralise the base Concentration of HCIO4 = = 0.09923 M Calculate the percentage purity of codeine phosphate. Explain your reasoning clearly

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Question

PEY
FOS
A batch of codeine phosphate powder was analysed according to the BP (1999) method
described below.
"Dissolve 0.350 g in a mixture of 10 mL anhydrous acetic acid and 20 mL of 1,4-dioxan
R. Titrate with 0.1 M perchloric acid (MM 100.46 g/mol) using 0.05 mL of crystal violet
solution R as indicator."
The following results were obtained:
Weight of powder taken for analysis
= 0.3495 g
= 8.53 mL
Volume of 0.1 M HClO4 required to neutralise the base
Concentration of HCIO4
= 0.09923 M
Calculate the percentage purity of codeine phosphate. Explain your reasoning clearly.

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