(a) (b) O (d) (2) If acetyl-CoA were labeled with ¹4℃ at carbonyl group, and then were used as the substrate for the citric acid cycle. Which of the following intermediates would be produced during the first round of the cycle contains the label at the correct position? OH H | | -oc-c-c−CH,-CO2 I I H CO, OH H T O,C-C–C–CH,-CO, I I H CO, OH H II O,C-C–C–CH, CO I T H CO2 OH H `O,C–C–C–CH2-CO I I H CO2 OH H `O,C-C-C-CH2-CO I I H CO,
(a) (b) O (d) (2) If acetyl-CoA were labeled with ¹4℃ at carbonyl group, and then were used as the substrate for the citric acid cycle. Which of the following intermediates would be produced during the first round of the cycle contains the label at the correct position? OH H | | -oc-c-c−CH,-CO2 I I H CO, OH H T O,C-C–C–CH,-CO, I I H CO, OH H II O,C-C–C–CH, CO I T H CO2 OH H `O,C–C–C–CH2-CO I I H CO2 OH H `O,C-C-C-CH2-CO I I H CO,
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter25: Nitrogen Acquisition And Amino Acid Metabolism
Section: Chapter Questions
Problem 22P
Related questions
Question
![**Citric Acid Cycle Intermediate Identification**
**Question:**
If acetyl-CoA were labeled with \(^{14}C\) at the carbonyl group, and then were used as the substrate for the citric acid cycle, which of the following intermediates would be produced during the first round of the cycle containing the label at the correct position?
**Options:**
**(a)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\text{C} - \text{C} - \ ^*{\text{C}} - \text{C} - \text{CH}_2 - \text{CO}_2^{-} \\
\vert \\
\text{H} \\
\text{CO}_2^{-}
\end{array}
\]
**(b)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\text{C} - \text{C} - \text{C} - \ ^*{\text{CH}_2} - \text{CO}_2^{-} \\
\vert \\
\text{H} \\
\text{CO}_2^{-}
\end{array}
\]
**(c)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\text{C} - \text{C} - \text{C} - \text{CH}_2 - \ ^*{\text{CO}_2^{-}} \\
\vert \\
\text{H} \\
\text{CO}_2^{-}
\end{array}
\]
**(d)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\text{C} - \ ^*{\text{C}} - \text{C} - \text{C} - \text{CH}_2 - \text{CO}_2^{-} \\
\vert \\
\text{H} \\
\text{CO}_2^{-}
\end{array}
\]
**(e)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fc62819af-1f81-4d59-bfb3-1ca1702855ed%2Fbd536828-37c1-4604-a069-381ecaec6518%2F2uqov35_processed.png&w=3840&q=75)
Transcribed Image Text:**Citric Acid Cycle Intermediate Identification**
**Question:**
If acetyl-CoA were labeled with \(^{14}C\) at the carbonyl group, and then were used as the substrate for the citric acid cycle, which of the following intermediates would be produced during the first round of the cycle containing the label at the correct position?
**Options:**
**(a)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\text{C} - \text{C} - \ ^*{\text{C}} - \text{C} - \text{CH}_2 - \text{CO}_2^{-} \\
\vert \\
\text{H} \\
\text{CO}_2^{-}
\end{array}
\]
**(b)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\text{C} - \text{C} - \text{C} - \ ^*{\text{CH}_2} - \text{CO}_2^{-} \\
\vert \\
\text{H} \\
\text{CO}_2^{-}
\end{array}
\]
**(c)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\text{C} - \text{C} - \text{C} - \text{CH}_2 - \ ^*{\text{CO}_2^{-}} \\
\vert \\
\text{H} \\
\text{CO}_2^{-}
\end{array}
\]
**(d)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\text{C} - \ ^*{\text{C}} - \text{C} - \text{C} - \text{CH}_2 - \text{CO}_2^{-} \\
\vert \\
\text{H} \\
\text{CO}_2^{-}
\end{array}
\]
**(e)**
\[
\begin{array}{c}
\text{OH} \\
\vert \\
\text{O}_2\
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