a) b) c) OH Br- CH3 CrO₂ OH Br H₂SO, A CrO, H₂SOA HNO₂ H₂SO4 yns ebosib bns LAH NaBH Fe HCI

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Chapter1: Chemical Foundations
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Predict major products of these reactions
### Chemical Reaction Exercises

This section outlines a series of organic chemistry reactions involving different reagents. The exercises illustrate transformations using oxidizing and reducing agents.

#### a) Reaction with Chromic Acid

**Substrate:**  
- Aromatic compound with a methyl group (toluene derivative).

**Reagents:**  
- \(\text{CrO}_3\) (Chromium trioxide)
- \(\text{H}_2\text{SO}_4\) (Sulfuric acid)
- Δ (Heat)

**Process:**
- This setup suggests an oxidation reaction, typically leading to the conversion of a methyl group to a carboxylic acid in aromatic compounds.

**Product (likely):**
- Benzoic acid.

#### b) Oxidation of Diol

**Substrate:**  
- Cyclohexane derivative with two hydroxyl groups (diol).

**Reagents:**  
- \(\text{CrO}_3\) (Chromium trioxide)
- \(\text{H}_2\text{SO}_4\) (Sulfuric acid)

**Process:**
- The diol is likely oxidized to a diketone or an acid, depending on the reaction conditions.

#### c) Nitration of Dibromoarene

**Substrate:**  
- Aromatic compound with two bromine substituents (dibromoarene).

**Reagents:**  
- \(\text{HNO}_3\) (Nitric acid)
- \(\text{H}_2\text{SO}_4\) (Sulfuric acid)

**Additional Processes:**
- **Reduction:**
  - Reductive conditions with Fe (iron) and \(\text{HCl}\) (hydrochloric acid) are indicated, suggesting a reduction of nitro groups to amines.

------

These exercises demonstrate fundamental organic transformations and are crucial for understanding the underlying principles of organic synthesis.
Transcribed Image Text:### Chemical Reaction Exercises This section outlines a series of organic chemistry reactions involving different reagents. The exercises illustrate transformations using oxidizing and reducing agents. #### a) Reaction with Chromic Acid **Substrate:** - Aromatic compound with a methyl group (toluene derivative). **Reagents:** - \(\text{CrO}_3\) (Chromium trioxide) - \(\text{H}_2\text{SO}_4\) (Sulfuric acid) - Δ (Heat) **Process:** - This setup suggests an oxidation reaction, typically leading to the conversion of a methyl group to a carboxylic acid in aromatic compounds. **Product (likely):** - Benzoic acid. #### b) Oxidation of Diol **Substrate:** - Cyclohexane derivative with two hydroxyl groups (diol). **Reagents:** - \(\text{CrO}_3\) (Chromium trioxide) - \(\text{H}_2\text{SO}_4\) (Sulfuric acid) **Process:** - The diol is likely oxidized to a diketone or an acid, depending on the reaction conditions. #### c) Nitration of Dibromoarene **Substrate:** - Aromatic compound with two bromine substituents (dibromoarene). **Reagents:** - \(\text{HNO}_3\) (Nitric acid) - \(\text{H}_2\text{SO}_4\) (Sulfuric acid) **Additional Processes:** - **Reduction:** - Reductive conditions with Fe (iron) and \(\text{HCl}\) (hydrochloric acid) are indicated, suggesting a reduction of nitro groups to amines. ------ These exercises demonstrate fundamental organic transformations and are crucial for understanding the underlying principles of organic synthesis.
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