(a) AG for transport of a proton from the mitochondrial matrix (inside) to the intermembrane space (outside). Show your work. Recall that pH = -log[H*]. calculate the Δψ = -170mV T = 25°C R = 8.3145 J.K-¹.mol-1 F = 96,485 J. V-₁.mol-¹
(a) AG for transport of a proton from the mitochondrial matrix (inside) to the intermembrane space (outside). Show your work. Recall that pH = -log[H*]. calculate the Δψ = -170mV T = 25°C R = 8.3145 J.K-¹.mol-1 F = 96,485 J. V-₁.mol-¹
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question
calculate part a
![During the process of oxidative phosphorylation the electron transport chain couples the
movement of electrons to the pumping of protons (H+) into the intermembrane space of
the mitochondria (left side of graphic below). This reaction establishes a protonmotive
force that can then be utilized to synthesize ATP by a molecular machine called the
ATP-synthase (right side of graphic). ATP-synthase is an integral membrane protein
found within the inner mitochondrial membrane. The pH of the mitochondrial matrix
(inside) is ~ 7.8, whereas the pH of the intermembrane space of the mitochondria
(outside) is ~7.1.
cytoplasm
intermembrane H²
space
Δψ = -170mV
T = 25°C
NADH
NAD+
matrix
H+
R = 8.3145 J.K-1.mol-1
F = 96,485 J. V-1.mol-¹
H*
H+
ADP
H*
ATP
high [44]
low [49]
ATP
synthase
(a)
AG for transport of a proton from the mitochondrial matrix (inside) to the
intermembrane space (outside). Show your work.
Recall that pH = -log[H*].
H+
calculate the](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fd6957468-6fb1-4659-9083-987b06676d6d%2Ff7b13fb7-bb54-4001-ae45-5ae7b6b077df%2Fb1sic3f_processed.jpeg&w=3840&q=75)
Transcribed Image Text:During the process of oxidative phosphorylation the electron transport chain couples the
movement of electrons to the pumping of protons (H+) into the intermembrane space of
the mitochondria (left side of graphic below). This reaction establishes a protonmotive
force that can then be utilized to synthesize ATP by a molecular machine called the
ATP-synthase (right side of graphic). ATP-synthase is an integral membrane protein
found within the inner mitochondrial membrane. The pH of the mitochondrial matrix
(inside) is ~ 7.8, whereas the pH of the intermembrane space of the mitochondria
(outside) is ~7.1.
cytoplasm
intermembrane H²
space
Δψ = -170mV
T = 25°C
NADH
NAD+
matrix
H+
R = 8.3145 J.K-1.mol-1
F = 96,485 J. V-1.mol-¹
H*
H+
ADP
H*
ATP
high [44]
low [49]
ATP
synthase
(a)
AG for transport of a proton from the mitochondrial matrix (inside) to the
intermembrane space (outside). Show your work.
Recall that pH = -log[H*].
H+
calculate the
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