A 74-year-old man is admitted with a myocardial infarction and a severe acute cardiac arrhythmia. You decide to give lidocaine to correct the arrhythmia. A continuous intravenous infusion of lidocaine, 1.92 mg/min, is started at 8 AM. The pharmacokinetic parameters of lidocaine are: Vd 77 L; clearance 640 mL/min; half-life 1.4 h. What is the expected steady-state plasma concentration? a. 40 mg/L b. 0.025 mg/L C. 3.46 mg/L d. 7.2 mg/L e. 3.0 mg/l
A 74-year-old man is admitted with a myocardial infarction and a severe acute cardiac arrhythmia. You decide to give lidocaine to correct the arrhythmia. A continuous intravenous infusion of lidocaine, 1.92 mg/min, is started at 8 AM. The pharmacokinetic parameters of lidocaine are: Vd 77 L; clearance 640 mL/min; half-life 1.4 h. What is the expected steady-state plasma concentration? a. 40 mg/L b. 0.025 mg/L C. 3.46 mg/L d. 7.2 mg/L e. 3.0 mg/l
Chapter23: Pediatric Intravenous Medications
Section: Chapter Questions
Problem 1.2P
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Question
![A 74-year-old man is admitted with a myocardial infarction and a severe acute cardiac arrhythmia. You
decide to give lidocaine to correct the arrhythmia. A continuous intravenous infusion of lidocaine, 1.92
mg/min, is started at 8 AM. The pharmacokinetic parameters of lidocaine are: Vd 77 L; clearance 640
mL/min; half-life 1.4 h. What is the expected steady-state plasma concentration?
a.
40 mg/L
b.
0.025 mg/L
C.
3.46 mg/L
d.
7.2 mg/L
e.
3.0 mg/L](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F6e909818-227d-468d-b1c0-fc3939e65de9%2Fb557bba5-13bc-491f-8bf2-d57da7961738%2Fx6ts7tn_processed.jpeg&w=3840&q=75)
Transcribed Image Text:A 74-year-old man is admitted with a myocardial infarction and a severe acute cardiac arrhythmia. You
decide to give lidocaine to correct the arrhythmia. A continuous intravenous infusion of lidocaine, 1.92
mg/min, is started at 8 AM. The pharmacokinetic parameters of lidocaine are: Vd 77 L; clearance 640
mL/min; half-life 1.4 h. What is the expected steady-state plasma concentration?
a.
40 mg/L
b.
0.025 mg/L
C.
3.46 mg/L
d.
7.2 mg/L
e.
3.0 mg/L
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