A 59 year old woman comes to the physician because of a 3 day history of decreased urine output . She underwent cadaveric renal transplantation. 10 weeks ago, she has hypertension and type-2 diabetes mellitus. She takes immunosuppressive medications including azathioprine, prednisone and tacrolimus.. Physical examination shows tenderness over the allograft. Serum studies show increased urine nitrogen and increased creatinine concentrations. This patients condition is produced by a specific effector cell that targets the transplanted tissue for destruction through the recognition of foreign MHC class 1 antigens. This effector cell most likely expresses and produces which of the following ?                 Effector Cell Expression.                             Effector Cell Production (A) CD3 and CD4.                                            Interleukin 2(IL-2) and interferon gamma (B) CD3 and CD 4.                                           IL-4, IL-5 and IL-10 (C) CD3 and CD 8.                                           IL-4, IL-5 and IL-10 (D) CD 3 and CD 8.                                          Performing and granzymes (E) CD 10 and CD 24.                                                IgE

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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(41) A 59 year old woman comes to the physician because of a 3 day history of decreased urine output . She underwent cadaveric renal transplantation. 10 weeks ago, she has hypertension and type-2 diabetes mellitus. She takes immunosuppressive medications including azathioprine, prednisone and tacrolimus.. Physical examination shows tenderness over the allograft. Serum studies show increased urine nitrogen and increased creatinine concentrations. This patients condition is produced by a specific effector cell that targets the transplanted tissue for destruction through the recognition of foreign MHC class 1 antigens. This effector cell most likely expresses and produces which of the following ?

                Effector Cell Expression.                             Effector Cell Production

(A) CD3 and CD4.                                            Interleukin 2(IL-2) and interferon gamma

(B) CD3 and CD 4.                                           IL-4, IL-5 and IL-10

(C) CD3 and CD 8.                                           IL-4, IL-5 and IL-10

(D) CD 3 and CD 8.                                          Performing and granzymes

(E) CD 10 and CD 24.                                                IgE

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