A 57 year-old male patient who has a longstanding history of hypertension, type 2 diabetes and hyperlipidemia. He presents with a chief complaint of nausea, shortness of breath, lower extremity edema and abdominal swelling. He is 5 feet and 6 inches tall and weighs 77.7 kilograms (Body Surface Area: 1.90). His blood pressure is 165/92 mmHg, heart rate is 97 beats per minute. Blood has drawn and urine is collected for various clinical chemistry tests. Laboratory Data Urine Creatinine: 88 mg/dL Urine Volume: 3,777 mL/24 hrs Plasma Creatinine: 4.75 mg/dL Urea Nitrogen: 170 mg/dL Blood Uric Acid 11.7 mg/dL Questions: 1. Given these data, what is the Creatinine Clearance of this patient? What are the possibilities for his lower extremity edema? What is/are the probable cause/s for the elevated Creatinine and Urea N? 2. 3.

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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A 57 year-old male patient who has a longstanding history of hypertension, type 2 diabetes and
hyperlipidemia. He presents with a chief complaint of nausea, shortness of breath, lower extremity
edema and abdominal swelling. He is 5 feet and 6 inches tall and weighs 77.7 kilograms (Body
Surface Area: 1.90). His blood pressure is 165/92 mmHg, heart rate is 97 beats per minute. Blood
has drawn and urine is collected for various clinical chemistry tests.
Laboratory Data
Urine Creatinine:
88 mg/dL
Urine Volume:
3,777 mL/24 hrs
Plasma Creatinine:
4.75 mg/dL
Urea Nitrogen:
170 mg/dL
Blood Uric Acid
11.7 mg/dL
Questions:
1.
Given these data, what is the Creatinine Clearance of this patient?
What are the possibilities for his lower extremity edema?
What is/are the probable cause/s for the elevated Creatinine and Urea N?
2.
3.
Transcribed Image Text:A 57 year-old male patient who has a longstanding history of hypertension, type 2 diabetes and hyperlipidemia. He presents with a chief complaint of nausea, shortness of breath, lower extremity edema and abdominal swelling. He is 5 feet and 6 inches tall and weighs 77.7 kilograms (Body Surface Area: 1.90). His blood pressure is 165/92 mmHg, heart rate is 97 beats per minute. Blood has drawn and urine is collected for various clinical chemistry tests. Laboratory Data Urine Creatinine: 88 mg/dL Urine Volume: 3,777 mL/24 hrs Plasma Creatinine: 4.75 mg/dL Urea Nitrogen: 170 mg/dL Blood Uric Acid 11.7 mg/dL Questions: 1. Given these data, what is the Creatinine Clearance of this patient? What are the possibilities for his lower extremity edema? What is/are the probable cause/s for the elevated Creatinine and Urea N? 2. 3.
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