A 50-year-old man comes to the physician because of a cough productive of large quantities of mucus for 6 months. He has smoked 1 pack of cigarettes daily for 25 years. Which of the following cell types is the most likely cause of the increase in this patient's secretion of mucus? (A) Columnar ciliated epithelial cells (B) Goblet cells (C) Interstitial cells (D) Macrophages (E) Pneumocyte epithelial cells

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