A 10-month-old Central American child was referred to the laboratory for testing after being seen by a pediatrician. The phlebotomist noted that the child was very pale and listless. The laboratory tests results: Hb 5.6 g/dl Hct 24% RBC 3.5 X 109/L WBC 10.5 X109/L MCV 68.6fL MCH 16pg 23g/dl 200 X 109/L МСНС Platelet count Reticulocyte count 0.5% 465 µg/dl 40 µg/dl 0.9 mg/dl TIBC Serum iron Total serum bilirubin Saturation of transferrin 8.6% The blood film for this patient was showed like the following 1. What category of anemia is suggested by the morphology of the RBCS on the peripheral blood smear? 2. What laboratory assays would be of additional value in establishing the diagnosis? 3. What is the most probable cause of the patient's anemia?

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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V 7:19
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A 10-month-old Central American child was referred to the laboratory for testing after being
seen by a pediatrician. The phlebotomist noted that the child was very pale and listless.
The laboratory tests results:
Hb
5.6 g/dl
Hct
24%
RBC
3.5 X 109/L
WBC
10.5 X109/L
MCV
68.6fL
16pg
23g/dl
200 X 109/L
МСН
МСНС
Platelet count
Reticulocyte count
TIBC
0.5%
465 µg/dl
40 ug/dl
0.9 mg/dl
Serum iron
Total serum bilirubin
Saturation of transferrin
8.6%
The blood film for this patient was showed like the following
1. What category of anemia is suggested by the morphology of the RBCS on the
peripheral blood smear?
2. What laboratory assays would be of additional value in establishing the diagnosis?
3. What is the most probable cause of the patient's anemia?
4. How can these conditions affect the hematopoietic system?
5. How would you describe his anemia morphologically?
6. Do this patient laboratory test results and clinical history indicate that a bone marrow
examination is necessary? Why?
7. What do you expected the treatment will be for this patient?
Transcribed Image Text:V 7:19 assignment 1.pdf A 10-month-old Central American child was referred to the laboratory for testing after being seen by a pediatrician. The phlebotomist noted that the child was very pale and listless. The laboratory tests results: Hb 5.6 g/dl Hct 24% RBC 3.5 X 109/L WBC 10.5 X109/L MCV 68.6fL 16pg 23g/dl 200 X 109/L МСН МСНС Platelet count Reticulocyte count TIBC 0.5% 465 µg/dl 40 ug/dl 0.9 mg/dl Serum iron Total serum bilirubin Saturation of transferrin 8.6% The blood film for this patient was showed like the following 1. What category of anemia is suggested by the morphology of the RBCS on the peripheral blood smear? 2. What laboratory assays would be of additional value in establishing the diagnosis? 3. What is the most probable cause of the patient's anemia? 4. How can these conditions affect the hematopoietic system? 5. How would you describe his anemia morphologically? 6. Do this patient laboratory test results and clinical history indicate that a bone marrow examination is necessary? Why? 7. What do you expected the treatment will be for this patient?
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