9. 4-Methyl pyrazole has been developed as a long-acting and less toxic alternative to ethanol in the treatment of ethylene gly- col poisoning. Shown is a Lineweaver-Burk plot of the inhi-

Introduction to Chemical Engineering Thermodynamics
8th Edition
ISBN:9781259696527
Author:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Publisher:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Chapter1: Introduction
Section: Chapter Questions
Problem 1.1P
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9. 4-Methyl pyrazole has been developed as a long-acting and less
toxic alternative to ethanol in the treatment of ethylene gly-
col poisoning. Shown is a Lineweaver-Burk plot of the inhi-
bition of alcohol dehydrogenase by various concentrations of
4-methyl pyrazole. What type of inhibition appears to be exhib-
ited by this molecule?
3.0
6+
->
0
1
[EtOH]
2.0
1.0
0.2
[4-MP] μM
Transcribed Image Text:9. 4-Methyl pyrazole has been developed as a long-acting and less toxic alternative to ethanol in the treatment of ethylene gly- col poisoning. Shown is a Lineweaver-Burk plot of the inhi- bition of alcohol dehydrogenase by various concentrations of 4-methyl pyrazole. What type of inhibition appears to be exhib- ited by this molecule? 3.0 6+ -> 0 1 [EtOH] 2.0 1.0 0.2 [4-MP] μM
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