8. Which type of blood cell is affected in sickle cell anemia? How does the number and appearance of this cell type compare between the sickle cell slide and the normal blood slide?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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8. Which type of blood cell is affected in sickle cell anemia? How does the number and
appearance of this cell type compare between the sickle cell slide and the normal blood slide?
Transcribed Image Text:8. Which type of blood cell is affected in sickle cell anemia? How does the number and appearance of this cell type compare between the sickle cell slide and the normal blood slide?
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Sickle cell anemia is one of the group of disorders known as sickle cell disease. This disorder affects hemoglobin, a protein which carries oxygen through the body. Hemoglobin consist of  two identical α and two identical β chains. In sickle cell anemia, the amino acid glutamate present at the 6th position in the β-chain of hemoglobin is replaced by amino acid valine.

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