8. Using the provided chart, predict the proton ¹H NMR spectrum of acetaminophen Assignment a b C d e H3C Expected ppm H H "Ha Expected integration Expected multiplicity

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**Question 8: NMR Spectrum Prediction of Acetaminophen**

Using the provided chart, predict the proton \( ^1H \) NMR spectrum of acetaminophen.

**Chemical Structure:**

The structure of acetaminophen is provided in the diagram with labeled hydrogen atoms: 
- \( H_a \) corresponds to the methyl group \( CH_3 \) attached to the nitrogen.
- \( H_b \), \( H_c \), \( H_d \), and \( H_e \) refer to the aromatic hydrogens on the benzene ring. 

**Table for Spectrum Prediction:**

| Assignment | Expected ppm | Expected integration | Expected multiplicity |
|------------|--------------|----------------------|-----------------------|
| a          |              |                      |                       |
| b          |              |                      |                       |
| c          |              |                      |                       |
| d          |              |                      |                       |
| e          |              |                      |                       |

**Instructions:**

Fill in the table with predictions based on the molecular structure and known chemical shift data. Consider factors like electronic environment and neighboring hydrogen atoms to approximate the expected ppm, integration, and multiplicity for each type of hydrogen atom.
Transcribed Image Text:**Question 8: NMR Spectrum Prediction of Acetaminophen** Using the provided chart, predict the proton \( ^1H \) NMR spectrum of acetaminophen. **Chemical Structure:** The structure of acetaminophen is provided in the diagram with labeled hydrogen atoms: - \( H_a \) corresponds to the methyl group \( CH_3 \) attached to the nitrogen. - \( H_b \), \( H_c \), \( H_d \), and \( H_e \) refer to the aromatic hydrogens on the benzene ring. **Table for Spectrum Prediction:** | Assignment | Expected ppm | Expected integration | Expected multiplicity | |------------|--------------|----------------------|-----------------------| | a | | | | | b | | | | | c | | | | | d | | | | | e | | | | **Instructions:** Fill in the table with predictions based on the molecular structure and known chemical shift data. Consider factors like electronic environment and neighboring hydrogen atoms to approximate the expected ppm, integration, and multiplicity for each type of hydrogen atom.
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