8. How many grams of sodium chloride should be used in compounding the prescription below? R Salt B chloride Sodium chloride Purified water ad 2% A. 0.174 g B. 0.270 g C. 0.150 g D. 0.550 g q.s. 30 mL Make isotonic solution Sig. Use as directed in the eye. E-value of Salt B is 0.20
8. How many grams of sodium chloride should be used in compounding the prescription below? R Salt B chloride Sodium chloride Purified water ad 2% A. 0.174 g B. 0.270 g C. 0.150 g D. 0.550 g q.s. 30 mL Make isotonic solution Sig. Use as directed in the eye. E-value of Salt B is 0.20
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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![**Question:**
8. How many grams of sodium chloride should be used in compounding the prescription below?
- **R**
- Salt B chloride 2%
- Sodium chloride q.s.
- Purified water ad 30 mL
- Make isotonic solution
- Sig. Use as directed in the eye.
- **E-value of Salt B is 0.20**
**Options:**
- A. 0.174 g
- B. 0.270 g
- C. 0.150 g
- D. 0.550 g
---
**Explanation:**
To create an isotonic solution for ophthalmic use, the E-value of the active ingredient (Salt B) is considered. The goal is to achieve a solution that matches the osmotic pressure of body fluids. The E-value indicates the sodium chloride equivalent: how much sodium chloride 1 gram of the drug is equivalent to in terms of tonicity.
1. Calculate the amount of sodium chloride needed for tonicity.
2. Consider the percentage and E-value provided.
3. Use these to determine the appropriate option that represents the correct weight in grams of sodium chloride required.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F7da53e7c-0f2c-4a91-b9de-2c66171dec7e%2F7c5ec696-cb08-4734-a89d-efc625ce2106%2Fqusyyjc_processed.png&w=3840&q=75)
Transcribed Image Text:**Question:**
8. How many grams of sodium chloride should be used in compounding the prescription below?
- **R**
- Salt B chloride 2%
- Sodium chloride q.s.
- Purified water ad 30 mL
- Make isotonic solution
- Sig. Use as directed in the eye.
- **E-value of Salt B is 0.20**
**Options:**
- A. 0.174 g
- B. 0.270 g
- C. 0.150 g
- D. 0.550 g
---
**Explanation:**
To create an isotonic solution for ophthalmic use, the E-value of the active ingredient (Salt B) is considered. The goal is to achieve a solution that matches the osmotic pressure of body fluids. The E-value indicates the sodium chloride equivalent: how much sodium chloride 1 gram of the drug is equivalent to in terms of tonicity.
1. Calculate the amount of sodium chloride needed for tonicity.
2. Consider the percentage and E-value provided.
3. Use these to determine the appropriate option that represents the correct weight in grams of sodium chloride required.
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