8. Consider the structure of Quinine, an antimalarial drug below with an optical rotation of -165°. (a) Draw the structure and identify (by a star) all stereogenic centres present in the Quinine structure. (b) Calculate the ee of the solution with the following [a] values: -50 and -120 (c) For each calculated ee, compute percentage of each enantiomer present. (d) What is the enantiomer of Quinine? (e) If the solution contains 80% quinine and 20% of it enantiomer, what is the ee of the solution?

8. Consider the structure of Quinine, an antimalarial drug below with an optical rotation of -165°. (a) Draw the structure and identify (by a star) all stereogenic centres present in the Quinine structure. (b) Calculate the ee of the solution with the following [a] values: -50 and -120 (c) For each calculated ee, compute percentage of each enantiomer present. (d) What is the enantiomer of Quinine? (e) If the solution contains 80% quinine and 20% of it enantiomer, what is the ee of the solution?

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Question

8. Consider the structure of Quinine, an antimalarial drug below with an optical
rotation of -165°.
(a) Draw the structure and identify (by a star) all stereogenic centres present in the
Quinine structure.
(b) Calculate the ee of the solution with the following [a] values: -50 and -120
(c) For each calculated ee, compute percentage of each enantiomer present.
(d) What is the enantiomer of Quinine?
(e) If the solution contains 80% quinine and 20% of it enantiomer, what is the ee of
the solution?
Но.
H3CO.

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