Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
![**Organic Chemistry Exercise: Benzene Derivatives Synthesis**
**Problem Statement:**
7. Synthesize ONE of the following benzene derivatives starting from benzene.
**Chemical Structure:**
The diagram illustrates a benzene ring with three substituents:
- A fluorine (F) atom is attached to the first carbon.
- A chlorine (Cl) atom is attached to the third carbon.
- An iodine (I) atom is attached to the fourth carbon.
This is a multi-substituted benzene derivative requiring specific reactions to ensure the correct placement of each substituent. The synthesis may involve steps such as halogenation, directing group effects, and protection/deprotection strategies.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F6746fa6f-1856-443b-addc-ecae5d9da9b9%2Fb857037e-687c-4403-8944-b7a0d7804303%2F3o49cc_processed.jpeg&w=3840&q=75)
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