7. Amide bonds generated by decarboxylative condensation -OH HO + H₂O CO₂

Chemistry & Chemical Reactivity
10th Edition
ISBN:9781337399074
Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Publisher:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Chapter23: Carbon: Not Just Another Element
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What would be a plausible mechanism for this reaction

 

7. Amide bonds generated by
decarboxylative condensation
OH
HO
nghe H2O + CO2
Highly chemo-selective and stereo-selective
Works in water without catalyst
No special requirement for terminal amino acids
Transcribed Image Text:7. Amide bonds generated by decarboxylative condensation OH HO nghe H2O + CO2 Highly chemo-selective and stereo-selective Works in water without catalyst No special requirement for terminal amino acids
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