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7. A local ophthalmologist is treating one of his patients for a post-LASIK eye infection that is not responding to topical ciprofloxacin. These infections, although rare, can occur after laser in situ keratomileusis (LASIK) surgery for vision correction. The ophthalmologist prescribes 60 mL of a 2.5% amikacin sulfate isotonic solution, 2 drops in the affected eye every 2 hours. Amikacin sulfate USP (C22H43N5O13 2H₂SO4), m.w., 781.76, is an aminoglycoside-type antibiotic containing 3-ions. a) Determine the weight in grams of amikacin sulfate needed to prepare the solution. b) Calculate the sodium chloride equivalent (E value) for amikacin sulfate. c) Calculate the amount of sodium chloride needed to make the prepared solution isotonic. d) How many milliliters of 23.5% sodium chloride should be used to obtain the needed sodium chloride?

7. A local ophthalmologist is treating one of his patients for a post-LASIK eye infection that is not responding to topical ciprofloxacin. These infections, although rare, can occur after laser in situ keratomileusis (LASIK) surgery for vision correction. The ophthalmologist prescribes 60 mL of a 2.5% amikacin sulfate isotonic solution, 2 drops in the affected eye every 2 hours. Amikacin sulfate USP (C22H43N5O13 2H₂SO4), m.w., 781.76, is an aminoglycoside-type antibiotic containing 3-ions. a) Determine the weight in grams of amikacin sulfate needed to prepare the solution. b) Calculate the sodium chloride equivalent (E value) for amikacin sulfate. c) Calculate the amount of sodium chloride needed to make the prepared solution isotonic. d) How many milliliters of 23.5% sodium chloride should be used to obtain the needed sodium chloride?

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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7. A local ophthalmologist is treating one of his patients for a post-LASIK eye infection that is not responding to topical ciprofloxacin. These infections, although rare, can occur after laser in situ keratomileusis (LASIK) surgery for vision correction. The ophthalmologist prescribes 60 mL of a 2.5% amikacin sulfate isotonic solution, 2 drops in the affected eye every 2 hours. Amikacin sulfate USP (C22H43N5O13 2H₂SO4), m.w., 781.76, is an aminoglycoside-type antibiotic containing 3-ions. a) Determine the weight in grams of amikacin sulfate needed to prepare the solution. b) Calculate the sodium chloride equivalent (E value) for amikacin sulfate. c) Calculate the amount of sodium chloride needed to make the prepared solution isotonic. d) How many milliliters of 23.5% sodium chloride should be used to obtain the needed sodium chloride?
Transcribed Image Text:7. A local ophthalmologist is treating one of his patients for a post-LASIK eye infection that is not responding to topical ciprofloxacin. These infections, although rare, can occur after laser in situ keratomileusis (LASIK) surgery for vision correction. The ophthalmologist prescribes 60 mL of a 2.5% amikacin sulfate isotonic solution, 2 drops in the affected eye every 2 hours. Amikacin sulfate USP (C22H43N5O13 2H₂SO4), m.w., 781.76, is an aminoglycoside-type antibiotic containing 3-ions. a) Determine the weight in grams of amikacin sulfate needed to prepare the solution. b) Calculate the sodium chloride equivalent (E value) for amikacin sulfate. c) Calculate the amount of sodium chloride needed to make the prepared solution isotonic. d) How many milliliters of 23.5% sodium chloride should be used to obtain the needed sodium chloride?
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