7. A local ophthalmologist is treating one of his patients for a post-LASIK eye infection that is not responding to topical ciprofloxacin. These infections, although rare, can occur after laser in situ keratomileusis (LASIK) surgery for vision correction. The ophthalmologist prescribes 60 mL of a 2.5% amikacin sulfate isotonic solution, 2 drops in the affected eye every 2 hours. Amikacin sulfate USP (C22H43N5O13 2H₂SO4), m.w., 781.76, is an aminoglycoside-type antibiotic containing 3-ions. a) Determine the weight in grams of amikacin sulfate needed to prepare the solution. b) Calculate the sodium chloride equivalent (E value) for amikacin sulfate. c) Calculate the amount of sodium chloride needed to make the prepared solution isotonic. d) How many milliliters of 23.5% sodium chloride should be used to obtain the needed sodium chloride?

Chemistry
9th Edition
ISBN:9781133611097
Author:Steven S. Zumdahl
Publisher:Steven S. Zumdahl
Chapter11: Properties Of Solutions
Section: Chapter Questions
Problem 109AE: Patients undergoing an upper gastrointestinal tract laboratory test are typically given an X-ray...
icon
Related questions
Question

Can you give me a detailed step by step process of how to do this please, thank you !

7. A local ophthalmologist is treating one of his patients for a post-LASIK eye infection that is not
responding to topical ciprofloxacin. These infections, although rare, can occur after laser in situ
keratomileusis (LASIK) surgery for vision correction. The ophthalmologist prescribes 60 mL of a 2.5%
amikacin sulfate isotonic solution, 2 drops in the affected eye every 2 hours.
Amikacin sulfate USP (C22H43N5O13 2H₂SO4), m.w., 781.76, is an aminoglycoside-type antibiotic
containing 3-ions.
a) Determine the weight in grams of amikacin sulfate needed to prepare the solution.
b) Calculate the sodium chloride equivalent (E value) for amikacin sulfate.
c) Calculate the amount of sodium chloride needed to make the prepared solution isotonic.
d) How many milliliters of 23.5% sodium chloride should be used to obtain the needed sodium
chloride?
Transcribed Image Text:7. A local ophthalmologist is treating one of his patients for a post-LASIK eye infection that is not responding to topical ciprofloxacin. These infections, although rare, can occur after laser in situ keratomileusis (LASIK) surgery for vision correction. The ophthalmologist prescribes 60 mL of a 2.5% amikacin sulfate isotonic solution, 2 drops in the affected eye every 2 hours. Amikacin sulfate USP (C22H43N5O13 2H₂SO4), m.w., 781.76, is an aminoglycoside-type antibiotic containing 3-ions. a) Determine the weight in grams of amikacin sulfate needed to prepare the solution. b) Calculate the sodium chloride equivalent (E value) for amikacin sulfate. c) Calculate the amount of sodium chloride needed to make the prepared solution isotonic. d) How many milliliters of 23.5% sodium chloride should be used to obtain the needed sodium chloride?
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 5 steps

Blurred answer
Knowledge Booster
Solutions
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Chemistry
Chemistry
Chemistry
ISBN:
9781133611097
Author:
Steven S. Zumdahl
Publisher:
Cengage Learning
Chemistry
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry: An Atoms First Approach
Chemistry: An Atoms First Approach
Chemistry
ISBN:
9781305079243
Author:
Steven S. Zumdahl, Susan A. Zumdahl
Publisher:
Cengage Learning
Introduction to General, Organic and Biochemistry
Introduction to General, Organic and Biochemistry
Chemistry
ISBN:
9781285869759
Author:
Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:
Cengage Learning
Introductory Chemistry: A Foundation
Introductory Chemistry: A Foundation
Chemistry
ISBN:
9781337399425
Author:
Steven S. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning