7) Treatment of this ketone with basic D₂O leads to rapid replacement of two hydrogen atoms by deuterium. Explain. Then, more slowly, all other non-aromatic hydrogens except one are replaced. How is this possible, and which proton cannot be replaced?

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter19: Aldehydes And Ketones: Nucleophilic Addition Reactions
Section19.SE: Something Extra
Problem 41MP: Aldehydes and ketones react with thiols to yield thioacetals just as they react with alcohols to...
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7) Treatment of this ketone with basic D₂O leads to rapid replacement of two hydrogen atoms by
deuterium. Explain. Then, more slowly, all other non-aromatic hydrogens except one are replaced. How
is this possible, and which proton cannot be replaced?
oro
Transcribed Image Text:7) Treatment of this ketone with basic D₂O leads to rapid replacement of two hydrogen atoms by deuterium. Explain. Then, more slowly, all other non-aromatic hydrogens except one are replaced. How is this possible, and which proton cannot be replaced? oro
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