Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter5: Resonance
Section: Chapter Questions
Problem 8E
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Question
![**Educational Content: Identification of Reaction Chemistry**
---
**Question:**
Indicate the reaction chemistry and draw the most probable reactant for the reaction below:
---
**Explanation with Reaction Scheme:**
The reaction involves a Suzuki coupling, which is a cross-coupling reaction widely used in organic chemistry. Here is the detailed reaction scheme and the corresponding components:
1. **Reagents Involved:**
- On the left side, the first reactant is a compound with a boronic acid group (-BH), substituted on a benzene ring.
- Below this molecule, the second reactant is a compound with a bromine substituent (Br) on a furan ring.
- The catalyst used in this reaction is Pd(PPh₃)₄.
2. **Reaction Arrow:** Indicates the direction of the reaction from the reactants to the product.
3. **Product:** The resulting product is a compound with a benzene ring and a furan ring, connected by a carbon-carbon double bond, with a carbonyl group (C=O) on the benzene ring.
Below is the step-by-step process:
**Step 1**:
- The boronic acid compound undergoes activation.
**Step 2**:
- The palladium catalyst facilitates the cross-coupling with the brominated furan compound.
The successful completion of the Suzuki reaction leads to the formation of the final product.
**Reaction Illustration:**
[Reactant 1: Benzene ring with a boronic acid group]
+
[Reactant 2: Furan ring with a bromine substituent]
→ *Pd(PPh₃)₄*
[Product: Benzene ring connected via a carbon-carbon double bond to a furan ring with a carbonyl group on the benzene ring]
---
This transformation demonstrates the power of the Suzuki coupling in forming C-C bonds to assemble complex molecular structures, which are frequently seen in natural products and pharmaceuticals.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F2b33b01c-85ce-4633-885b-c121b306567e%2F0f90c543-4af5-4761-a9b2-c7afb9a43944%2Fh8yuto_processed.jpeg&w=3840&q=75)
Transcribed Image Text:**Educational Content: Identification of Reaction Chemistry**
---
**Question:**
Indicate the reaction chemistry and draw the most probable reactant for the reaction below:
---
**Explanation with Reaction Scheme:**
The reaction involves a Suzuki coupling, which is a cross-coupling reaction widely used in organic chemistry. Here is the detailed reaction scheme and the corresponding components:
1. **Reagents Involved:**
- On the left side, the first reactant is a compound with a boronic acid group (-BH), substituted on a benzene ring.
- Below this molecule, the second reactant is a compound with a bromine substituent (Br) on a furan ring.
- The catalyst used in this reaction is Pd(PPh₃)₄.
2. **Reaction Arrow:** Indicates the direction of the reaction from the reactants to the product.
3. **Product:** The resulting product is a compound with a benzene ring and a furan ring, connected by a carbon-carbon double bond, with a carbonyl group (C=O) on the benzene ring.
Below is the step-by-step process:
**Step 1**:
- The boronic acid compound undergoes activation.
**Step 2**:
- The palladium catalyst facilitates the cross-coupling with the brominated furan compound.
The successful completion of the Suzuki reaction leads to the formation of the final product.
**Reaction Illustration:**
[Reactant 1: Benzene ring with a boronic acid group]
+
[Reactant 2: Furan ring with a bromine substituent]
→ *Pd(PPh₃)₄*
[Product: Benzene ring connected via a carbon-carbon double bond to a furan ring with a carbonyl group on the benzene ring]
---
This transformation demonstrates the power of the Suzuki coupling in forming C-C bonds to assemble complex molecular structures, which are frequently seen in natural products and pharmaceuticals.
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