6. A 40-year-old woman was taken to a hospital by ambulance. She exhibited tangled consciousness, the smell of acctone from the mouth, rapid breathing, xcrostomia. Screening showed that the blood glucose concentration is 18 mmol/L (324 mg/ dL); ketone bodies-4.9 mmol/dL (norm 0.02-0.43). Urine contained ketone bodies. Arterial pH is 7.3. Based on the studies conducted, diabetic ketoacidosis was diagnosed. What metabolic changes could lead to the situation described above? For answer: a) suggest the type of diabetes and give the changes of hormonal status associated with diabctes mcllitus; b) list the main symptoms of the discase and explain their causes; c) draw the charts of lipid metabolism pathways in adipose tissue and liver with an acceleration leading to ketoacidosis:

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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muer the
xƏ DUR SUO
am the
Disequences UI
6. A 40-ycar-old woman was taken toa hospital by ambulance. She exhibited tangled
consciousness, the smell of acetone from the mouth, rapid breathing, xerostomia.
Screening showed that the blood glucose concentration is 18 mmol/L (324 mg/
dL); ketone bodies - 4.9 mmol/dL (norm 0.02-0.43). Urine contained ketone
bodics. Arterial pH is 7.3. Based on the studies conducted, diabetic ketoacidosis
was diagnosed. What metabolic changes could lead to the situation described
above? For answer:
a) suggest the type of diabetes and give the changes of hormonal status associated
with diabetes mcllitus;
b) list the main symptoms of the disease and explain their causes;
c) draw the charts of lipid metabolism pathways in adipose tissue and liver with
an acceleration leading to ketoacidosis;
d) name the immediate actions to improve the patient's condition.
IDD
Transcribed Image Text:muer the xƏ DUR SUO am the Disequences UI 6. A 40-ycar-old woman was taken toa hospital by ambulance. She exhibited tangled consciousness, the smell of acetone from the mouth, rapid breathing, xerostomia. Screening showed that the blood glucose concentration is 18 mmol/L (324 mg/ dL); ketone bodies - 4.9 mmol/dL (norm 0.02-0.43). Urine contained ketone bodics. Arterial pH is 7.3. Based on the studies conducted, diabetic ketoacidosis was diagnosed. What metabolic changes could lead to the situation described above? For answer: a) suggest the type of diabetes and give the changes of hormonal status associated with diabetes mcllitus; b) list the main symptoms of the disease and explain their causes; c) draw the charts of lipid metabolism pathways in adipose tissue and liver with an acceleration leading to ketoacidosis; d) name the immediate actions to improve the patient's condition. IDD
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