53. Which of the following is a genetic disorder caused by a mutation in only a single nucleotide pair? A. sickle-cell anemia B. lung cancer C. type Il diabetes D. HIV/AIDS 54. A depurination mutation may cause which of the following to occur? A. A purine is lost by hydrolysis. B. Two thymines stick to each other. C. A double strand DNA break occurs. D. A cytosine is converted into a uracil. 55. A deamination mutation may cause which of the following to occur? A. Two thymines stick to each other. B. A purine is lost by hydrolysis. C. A cytosine is converted into a uracil. D. A double strand DNA break occurs. 8 0

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**Exam Questions on Genetic Mutations and UV Light Exposure**

**53. Which of the following is a genetic disorder caused by a mutation in only a single nucleotide pair?**

A. Sickle-cell anemia  
B. Lung cancer  
C. Type II diabetes  
D. HIV/AIDS  

**54. A depurination mutation may cause which of the following to occur?**

A. A purine is lost by hydrolysis.  
B. Two thymines stick to each other.  
C. A double strand DNA break occurs.  
D. A cytosine is converted into a uracil.  

**55. A deamination mutation may cause which of the following to occur?**

A. Two thymines stick to each other.  
B. A purine is lost by hydrolysis.  
C. A cytosine is converted into a uracil.  
D. A double strand DNA break occurs.  

**56. What type of damage is often the result of excessive UV light exposure?**

A. Primer dimers  
B. Depurinations  
C. Helicase dimers  
D. Thymidine dimers  

**57. What generally occurs when a cell tries to fix double strand DNA breaks using nonhomologous end joining (hint: it may be a potential problem).**

A. New nucleotides are added.  
B. The DNA would then have three strands.  
C. Some of the nucleotides are lost.  
D. New nucleotides are added.
Transcribed Image Text:**Exam Questions on Genetic Mutations and UV Light Exposure** **53. Which of the following is a genetic disorder caused by a mutation in only a single nucleotide pair?** A. Sickle-cell anemia B. Lung cancer C. Type II diabetes D. HIV/AIDS **54. A depurination mutation may cause which of the following to occur?** A. A purine is lost by hydrolysis. B. Two thymines stick to each other. C. A double strand DNA break occurs. D. A cytosine is converted into a uracil. **55. A deamination mutation may cause which of the following to occur?** A. Two thymines stick to each other. B. A purine is lost by hydrolysis. C. A cytosine is converted into a uracil. D. A double strand DNA break occurs. **56. What type of damage is often the result of excessive UV light exposure?** A. Primer dimers B. Depurinations C. Helicase dimers D. Thymidine dimers **57. What generally occurs when a cell tries to fix double strand DNA breaks using nonhomologous end joining (hint: it may be a potential problem).** A. New nucleotides are added. B. The DNA would then have three strands. C. Some of the nucleotides are lost. D. New nucleotides are added.
**Quiz Questions on DNA Replication and Function**

45. The main form in which DNA exists in our cells is the ___________ form of DNA.
   - A. A
   - B. B
   - C. Z
   - D. W
   
46. DNA polymerase can correct some of the errors it makes. How does it do this?
   - A. It uses 3′ to 5′ helicase activity.
   - B. It uses 3′ to 5′ exonuclease activity.
   - C. It uses 5′ to 3′ exonuclease activity.
   - D. It uses 5′ to 3′ helicase activity.

47. What allows for a new Okazaki fragment to begin?
   - A. A promoter on the leading strand.
   - B. A single stranded binding protein on the leading strand.
   - C. A promoter on the lagging strand.
   - D. A probe on the lagging strand.

48. When is the lagging strand synthesized during DNA replication?
   - A. At the same time as the leading strand
   - B. After the leading strand
   - C. Before the leading strand
   - D. Before the Okazaki fragments

49. Besides polymerizing DNA, what other activity does DNA polymerase have (hint: it uses a different active site)?
   - A. transcribing
   - B. translating
   - C. proofreading
   - D. ligating

50. What is the function of telomerase?
   - A. It unwinds the DNA during replication.
   - B. It makes the lagging strand shorter.
   - C. It is the origin of DNA replication.
   - D. It adds repetitive sequences to the end of the template strand.

51. Which of the following cell types would be expected to have telomerase activity?
   - A. stem cells
   - B. cancer cells
   - C. germ cells (that make sperm or egg cells)
   - D. all of the above
   
52. Which enzyme unwinds/unzips the two strands of DNA during replication?
   - A. helicase
   - B. ligase
   - C. primase
   - D. lactase
Transcribed Image Text:**Quiz Questions on DNA Replication and Function** 45. The main form in which DNA exists in our cells is the ___________ form of DNA. - A. A - B. B - C. Z - D. W 46. DNA polymerase can correct some of the errors it makes. How does it do this? - A. It uses 3′ to 5′ helicase activity. - B. It uses 3′ to 5′ exonuclease activity. - C. It uses 5′ to 3′ exonuclease activity. - D. It uses 5′ to 3′ helicase activity. 47. What allows for a new Okazaki fragment to begin? - A. A promoter on the leading strand. - B. A single stranded binding protein on the leading strand. - C. A promoter on the lagging strand. - D. A probe on the lagging strand. 48. When is the lagging strand synthesized during DNA replication? - A. At the same time as the leading strand - B. After the leading strand - C. Before the leading strand - D. Before the Okazaki fragments 49. Besides polymerizing DNA, what other activity does DNA polymerase have (hint: it uses a different active site)? - A. transcribing - B. translating - C. proofreading - D. ligating 50. What is the function of telomerase? - A. It unwinds the DNA during replication. - B. It makes the lagging strand shorter. - C. It is the origin of DNA replication. - D. It adds repetitive sequences to the end of the template strand. 51. Which of the following cell types would be expected to have telomerase activity? - A. stem cells - B. cancer cells - C. germ cells (that make sperm or egg cells) - D. all of the above 52. Which enzyme unwinds/unzips the two strands of DNA during replication? - A. helicase - B. ligase - C. primase - D. lactase
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