51 > < Paragraph Styles Shirley was assigned to take Mr. Aletha to physical therapy. She helped Mr. Aletha into the wheelchair and took him down the hallway to the room where he was to receive strengthening exercises for his generalized muscle weakness. Mr. Aletha told Shirley that he often felt okay at the beginning of his therapy session but became weaker as the session progressed. Mr. Aletha was in the hospital because of this perplexing problem. One day Shirley went to Mr. Aletha's room to take him to therapy, but Mr. Aletha told her that the sessions were canceled: The therapy would not help his condition because he had myasthenia gravis. Shirley had heard about this disease but did not understand the physiology. She went to her anatomy text and began to read the chapters on muscle contraction and nerve transmission. Help her answer the following questions so she can put this puzzling disease in perspective. Voltage-gated Synaptic end bulb, Ca" channel Axon Action potential Motor neuron Synaptic. vesicles Synaptic cleft T-tubule Motor end plate Muscle fibers Neurotransmitter Neurotransmitter receptors W

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**Understanding Myasthenia Gravis: A Case Study and Diagram Explanation**

Shirley was assigned to take Mr. Aletha to physical therapy. She helped Mr. Aletha into the wheelchair and took him down the hallway to the room where he was to receive strengthening exercises for his generalized muscle weakness. Mr. Aletha told Shirley that he often felt okay at the beginning of his therapy session but became weaker as the session progressed. Mr. Aletha was in the hospital because of this perplexing problem. One day Shirley went to Mr. Aletha’s room to take him to therapy, but Mr. Aletha told her that the sessions were canceled: The therapy would not help his condition because he had myasthenia gravis. Shirley had heard about this disease but did not understand the physiology. She went to her anatomy text and began to read the chapters on muscle contraction and nerve transmission. Help her answer the following questions so she can put this puzzling disease in perspective.

**Diagram Explanation:**

The diagram shows the connection between a motor neuron and a muscle fiber. Here's a detailed breakdown:

- **Motor Neuron**: This is a nerve cell responsible for transmitting signals to muscle fibers.
- **Action Potential**: A nerve impulse that travels along the axon of the motor neuron.
- **Synaptic Vesicles**: These are small sacs within the neuron that contain neurotransmitters.
- **Synaptic Cleft**: The small gap between the motor neuron and the muscle fiber.
- **Voltage-gated Ca²⁺ Channel**: Channels that allow calcium ions to enter the neuron, triggering the release of neurotransmitters.
- **Neurotransmitter**: Chemicals released by the neuron into the synaptic cleft to transmit the nerve signal to the muscle.
- **Neurotransmitter Receptors**: Located on the muscle fiber, these receive the neurotransmitters, leading to muscle contraction.
- **T-tubule**: Part of the muscle fiber involved in transmitting the signal to enable contraction.

This process is critical for muscle contraction, and any disruptions, such as those caused by myasthenia gravis, can lead to muscle weakness.
Transcribed Image Text:**Understanding Myasthenia Gravis: A Case Study and Diagram Explanation** Shirley was assigned to take Mr. Aletha to physical therapy. She helped Mr. Aletha into the wheelchair and took him down the hallway to the room where he was to receive strengthening exercises for his generalized muscle weakness. Mr. Aletha told Shirley that he often felt okay at the beginning of his therapy session but became weaker as the session progressed. Mr. Aletha was in the hospital because of this perplexing problem. One day Shirley went to Mr. Aletha’s room to take him to therapy, but Mr. Aletha told her that the sessions were canceled: The therapy would not help his condition because he had myasthenia gravis. Shirley had heard about this disease but did not understand the physiology. She went to her anatomy text and began to read the chapters on muscle contraction and nerve transmission. Help her answer the following questions so she can put this puzzling disease in perspective. **Diagram Explanation:** The diagram shows the connection between a motor neuron and a muscle fiber. Here's a detailed breakdown: - **Motor Neuron**: This is a nerve cell responsible for transmitting signals to muscle fibers. - **Action Potential**: A nerve impulse that travels along the axon of the motor neuron. - **Synaptic Vesicles**: These are small sacs within the neuron that contain neurotransmitters. - **Synaptic Cleft**: The small gap between the motor neuron and the muscle fiber. - **Voltage-gated Ca²⁺ Channel**: Channels that allow calcium ions to enter the neuron, triggering the release of neurotransmitters. - **Neurotransmitter**: Chemicals released by the neuron into the synaptic cleft to transmit the nerve signal to the muscle. - **Neurotransmitter Receptors**: Located on the muscle fiber, these receive the neurotransmitters, leading to muscle contraction. - **T-tubule**: Part of the muscle fiber involved in transmitting the signal to enable contraction. This process is critical for muscle contraction, and any disruptions, such as those caused by myasthenia gravis, can lead to muscle weakness.
Certainly! Here is the transcription of the text for use on an educational website:

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5. Myasthenia gravis is an autoimmune disease in which the body's immune cells attack and destroy the acetylcholine (Ach) receptors in the motor end plates of muscles in the shoulder, neck, and face. When muscle do not contracts, muscle atrophy (loss of muscle mass) is caused by not using the muscles enough. Why would Mr. Aletha experience a progressive weakening even if he tries to do more exercise?

6. Do aerobic (endurance) and resistance exercises produce the same effect on muscles? How do endurance and anaerobic exercises normally enhance your ability to contract muscles?

---

There are no graphs or diagrams in the image.
Transcribed Image Text:Certainly! Here is the transcription of the text for use on an educational website: --- 5. Myasthenia gravis is an autoimmune disease in which the body's immune cells attack and destroy the acetylcholine (Ach) receptors in the motor end plates of muscles in the shoulder, neck, and face. When muscle do not contracts, muscle atrophy (loss of muscle mass) is caused by not using the muscles enough. Why would Mr. Aletha experience a progressive weakening even if he tries to do more exercise? 6. Do aerobic (endurance) and resistance exercises produce the same effect on muscles? How do endurance and anaerobic exercises normally enhance your ability to contract muscles? --- There are no graphs or diagrams in the image.
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