5. (WRF 27.18) A small spherical bead is used as a controlled drug-release capsule in the gastrointestinal system. A 0.10 cm diameter bead has a uniform initial concentration of 0.20 mmol/L of the drug griseofulvin (species A). The diffusion coefficient of griseofulvin within the bead material is 1.5x10-7 cm²/s. Upon release from the bead, the drug is immediately consumed so that the surface concentration is essentially zero. Using the concentration-time charts, determine the time it will take for concentration of the griseofulvin in the center of the bead to reach 10% of its initial value.

Introduction to Chemical Engineering Thermodynamics
8th Edition
ISBN:9781259696527
Author:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
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5. (WRF 27.18) A small spherical bead is used as a controlled drug-release capsule in the
gastrointestinal system. A 0.10 cm diameter bead has a uniform initial concentration of 0.20
mmol/L of the drug griseofulvin (species A). The diffusion coefficient of griseofulvin within the
bead material is 1.5x10-7 cm²/s. Upon release from the bead, the drug is immediately consumed
so that the surface concentration is essentially zero. Using the concentration-time charts,
determine the time it will take for concentration of the griseofulvin in the center of the bead to
reach 10% of its initial value.
Transcribed Image Text:5. (WRF 27.18) A small spherical bead is used as a controlled drug-release capsule in the gastrointestinal system. A 0.10 cm diameter bead has a uniform initial concentration of 0.20 mmol/L of the drug griseofulvin (species A). The diffusion coefficient of griseofulvin within the bead material is 1.5x10-7 cm²/s. Upon release from the bead, the drug is immediately consumed so that the surface concentration is essentially zero. Using the concentration-time charts, determine the time it will take for concentration of the griseofulvin in the center of the bead to reach 10% of its initial value.
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