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5. What amount (in ml) will you withdraw from the vial to deliver a single dose of the medication?

5. What amount (in ml) will you withdraw from the vial to deliver a single dose of the medication?

Phlebotomy Essentials
Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
Section: Chapter Questions
Problem 1SRQ
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I need #5 on this one please and you can answer #4 if you have time!

Antibiotic Injection Case You receive a RX order from a Physician for Ampicillin. The RX is for a child weighing 33 pounds. The child has a Gastrointestinal Infection. The doctor wants to give the injections by the IM route of administration. He has given the order for this to be given every 8 hours You quickly review your inventory and discover that you only have the 1-gram vials of Ampicillin in stock. Package Insert Please review the information from the Package insert for Directions for use and Dosage and indication sections and determine the following things? DIRECTIONS FOR USE 1. Is this Medication indicated for Gastrointestinal Infections? Use only freshly prepared solutions. Intramuscular and intravenous injections should be administered within one hour after preparation, since the potency may decrease significantly after this period. Parenteral drug products should be inspected visually for particulate mat- ter and discoloration prior to administration, whenever solution and container permit. For Intramuscular Use: Dissolve contents of a vial with the amount of Sterile Water for Injection, USP or Bacteriostatic Water for Injection, USP, listed in the table below: Recommended 2. Can it be given to a Pediatric patient? Label Claim 10515-143-00 125 mg 1.2 ml 10515-145-00 250 mg 1 ml 10515-146-00 500 mg 1.8 ml 10515-772-00 1 gram 3.5 ml 10515-140-00 2 grams 6.8 ml Amount of Diluent Withdrawable Concentration (in mg/ml) 125 mg 250 mg 250 mg 250 mg 250 mg NDC Volume 1 ml 1 mL 2 ml 4 ml 8 ml 3. What is the dose for a child weighing 33 pounds? Per Day? Per dose? While Ampicillin for Injection, USP 1 g and 2 g, are primarily for intravenous use, they may be administered intramuscularly when the 250 mg or 500 mg vials are unavailable. In such instances, dissolve in 3.5 or 6.8 mL Šterile Water for Injection, USP or Bacteriostatic Water for Injection, USP, respectively. The resulting solution will provide a concentration of 250 mg per ml. Ampicillin for Injection, USP 125 mg, is intended primarily for pediatric use. It also serves as a convenient dosage form when small parenteral doses of the antibiotic are required. Note: Bacteriostatic Water for Injection, USP is not to be used as a diluent when the product will be used in newborns. For Direct Intravenous Use: Add 5 mL Sterile Water for Injection, USP, or Bacteriostatic Water for Injection, USP to the 125 mg. 250 mg, and 500 mg vials and administer slowly over a 3- to 5- minute period. Ampicillin for Injection, USP1gor 29, may also be given by direct intravenous administration. Dissolve in 7.4 or 14.8 ml Sterile Water for Injection, USP, or Bacteriostatic Water for Injection, USP, respectively, and administer slowly over at least 10 to 15 min- utes. CAUTION: More rapid administration mav result in convulsive seizures.
Transcribed Image Text:Antibiotic Injection Case You receive a RX order from a Physician for Ampicillin. The RX is for a child weighing 33 pounds. The child has a Gastrointestinal Infection. The doctor wants to give the injections by the IM route of administration. He has given the order for this to be given every 8 hours You quickly review your inventory and discover that you only have the 1-gram vials of Ampicillin in stock. Package Insert Please review the information from the Package insert for Directions for use and Dosage and indication sections and determine the following things? DIRECTIONS FOR USE 1. Is this Medication indicated for Gastrointestinal Infections? Use only freshly prepared solutions. Intramuscular and intravenous injections should be administered within one hour after preparation, since the potency may decrease significantly after this period. Parenteral drug products should be inspected visually for particulate mat- ter and discoloration prior to administration, whenever solution and container permit. For Intramuscular Use: Dissolve contents of a vial with the amount of Sterile Water for Injection, USP or Bacteriostatic Water for Injection, USP, listed in the table below: Recommended 2. Can it be given to a Pediatric patient? Label Claim 10515-143-00 125 mg 1.2 ml 10515-145-00 250 mg 1 ml 10515-146-00 500 mg 1.8 ml 10515-772-00 1 gram 3.5 ml 10515-140-00 2 grams 6.8 ml Amount of Diluent Withdrawable Concentration (in mg/ml) 125 mg 250 mg 250 mg 250 mg 250 mg NDC Volume 1 ml 1 mL 2 ml 4 ml 8 ml 3. What is the dose for a child weighing 33 pounds? Per Day? Per dose? While Ampicillin for Injection, USP 1 g and 2 g, are primarily for intravenous use, they may be administered intramuscularly when the 250 mg or 500 mg vials are unavailable. In such instances, dissolve in 3.5 or 6.8 mL Šterile Water for Injection, USP or Bacteriostatic Water for Injection, USP, respectively. The resulting solution will provide a concentration of 250 mg per ml. Ampicillin for Injection, USP 125 mg, is intended primarily for pediatric use. It also serves as a convenient dosage form when small parenteral doses of the antibiotic are required. Note: Bacteriostatic Water for Injection, USP is not to be used as a diluent when the product will be used in newborns. For Direct Intravenous Use: Add 5 mL Sterile Water for Injection, USP, or Bacteriostatic Water for Injection, USP to the 125 mg. 250 mg, and 500 mg vials and administer slowly over a 3- to 5- minute period. Ampicillin for Injection, USP1gor 29, may also be given by direct intravenous administration. Dissolve in 7.4 or 14.8 ml Sterile Water for Injection, USP, or Bacteriostatic Water for Injection, USP, respectively, and administer slowly over at least 10 to 15 min- utes. CAUTION: More rapid administration mav result in convulsive seizures.
Dur nor pertoter unysis DOSAGE AND ADMINISTRATION Infections of the respiratory tract and soft tissues. Patients weighing 40 kg (88 Ibs) or more: 250 to 500 mg every 6 hours. Patients weighing less than 40 kg (88 Ibs): 25 to 50 mg/kg/day in equally divided doses at 6-to 8-hour intervals. Infections of the gastrointestinal and genitourinary tracts (including those caused by Neisseria gonorrhoeae in females). Patients weighing 40 kg (88 Ibs) or more: 500 mg every 6 hours. Patients weighing less than 40 kg (88 Ibs): 50 mg/kg/day in equally divided doses at 6-to 8-hour intervals. In the treatment of chronic urinary tract and intestinal infections, frequent bacteriological and clinical appraisal is necessary. Smaller doses than those recommended above should not be used. Higher doses should be used for stubborn or severe infections. In stubborn infections, therapy may be required for several weeks. It may be necessary to continue clinical and/or bacteriological follow-up for several months after cessation of therapy. Urethritis in males due to N. gonorrhoeae. Adults: Two doses of 500 mg each at an interval of 8 to 12 hours. Treatment may be repeated if necessary or extended if required. In the treatment of complications of gonorrheal urethritis, such as prostatitis and epididymitis, prolonged and intensive therapy is recommended. Cases of gonorrhea with a suspected primary lesion of syphilis should have darkfield examinations before receiving treatment. In all other cases where concomitant syphilis is suspected, monthly serological tests should be made for a minimum of four months. The doses for the preceding infections may be given by either the intra- muscular or intravenous route. A change to oral ampicillin may be made when appropriate. Bacterial Meningitis. Adults and children: 150 to 200 mg/kp/day in equally divided doses every 3 to 4 hours. (Treatment may be initiated with intravenous drip therapy and continued with intramuscular injections.) The doses for other infections may be given by either the intravenous or intramuscular route. Neonates (less than or equal to 28 days of postnatal age): Dosage should be based on Gestational age and Postnatal age according to Table 3. Table 3: Dosage in Neonates (less than or equal to 28 days of postnatal age) for Bacterial Meningitis and Septicemia Give the instructions for reconstitution of the 1-gram vial you have in stock? Give information on what diluent you will use, the amount and procedure for reconstitution of this vial 4. 5. What amount (in ml) will you withdraw from the vial to deliver a single dose of the medication?
Transcribed Image Text:Dur nor pertoter unysis DOSAGE AND ADMINISTRATION Infections of the respiratory tract and soft tissues. Patients weighing 40 kg (88 Ibs) or more: 250 to 500 mg every 6 hours. Patients weighing less than 40 kg (88 Ibs): 25 to 50 mg/kg/day in equally divided doses at 6-to 8-hour intervals. Infections of the gastrointestinal and genitourinary tracts (including those caused by Neisseria gonorrhoeae in females). Patients weighing 40 kg (88 Ibs) or more: 500 mg every 6 hours. Patients weighing less than 40 kg (88 Ibs): 50 mg/kg/day in equally divided doses at 6-to 8-hour intervals. In the treatment of chronic urinary tract and intestinal infections, frequent bacteriological and clinical appraisal is necessary. Smaller doses than those recommended above should not be used. Higher doses should be used for stubborn or severe infections. In stubborn infections, therapy may be required for several weeks. It may be necessary to continue clinical and/or bacteriological follow-up for several months after cessation of therapy. Urethritis in males due to N. gonorrhoeae. Adults: Two doses of 500 mg each at an interval of 8 to 12 hours. Treatment may be repeated if necessary or extended if required. In the treatment of complications of gonorrheal urethritis, such as prostatitis and epididymitis, prolonged and intensive therapy is recommended. Cases of gonorrhea with a suspected primary lesion of syphilis should have darkfield examinations before receiving treatment. In all other cases where concomitant syphilis is suspected, monthly serological tests should be made for a minimum of four months. The doses for the preceding infections may be given by either the intra- muscular or intravenous route. A change to oral ampicillin may be made when appropriate. Bacterial Meningitis. Adults and children: 150 to 200 mg/kp/day in equally divided doses every 3 to 4 hours. (Treatment may be initiated with intravenous drip therapy and continued with intramuscular injections.) The doses for other infections may be given by either the intravenous or intramuscular route. Neonates (less than or equal to 28 days of postnatal age): Dosage should be based on Gestational age and Postnatal age according to Table 3. Table 3: Dosage in Neonates (less than or equal to 28 days of postnatal age) for Bacterial Meningitis and Septicemia Give the instructions for reconstitution of the 1-gram vial you have in stock? Give information on what diluent you will use, the amount and procedure for reconstitution of this vial 4. 5. What amount (in ml) will you withdraw from the vial to deliver a single dose of the medication?
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