5. The reaction sequence shown below involves a Claisen condensation (step 1), followed by an aldol condensation (step 2). Draw the mechanisms of both reactions. (4) H3C H₂C COA COA (1) H3C COASH H3C COA COA (2) COASH OH OH COA

Q: You have learned two ways to make an alkyl benzene: Friedel–Craftsalkylation, and Friedel–Crafts…

A: Alkyl benzenes are the substituted benzene in which substituent is an alkyl group. Benzene undergoes…

Q: Show the mechanism and all products formed when benzoic anhydride is treated with the nucleophile…

A: The objective of the question is to understand the reaction mechanism and identify the products when…

Q: O Propose a retrosynthesis and then a synthesis for the transformation below. oh HO

A: Given is organic synthesis reaction.In this reaction reactant is Carboxylic acid and product is…

Q: H - да

A: Under the influence of dilute base, two molecules of an aldehyde containing at least one…

Q: Aldol Condensation For the following carbonyl compound, draw all possible enolates. Which is most…

A: The objective of the question is to understand the process of Aldol condensation, identify the most…

Q: Draw all products for aldol reaction

A: Aldol Reaction:  The reaction of enolate of an aldehyde or a ketone with the carbonyl of another…

Q: If the formula of an oxide of element X is X₂03, what is the formula of the chloride of X? (A) XC13…

A:

Q: compound, forming an enolate ion. The enolate ion has two resonance contributors. In the box on the…

A: Given is carbanion of ester molecule produce by removal of alpha proton.

Q: The by-product of the aldol reaction is not drawn here, what is it?

A:

Q: The right-hand side of this reaction shows the product of an aldol condensation. What are the…

A: Step 1: Step 2: Step 3: Step 4:

Q: Identify the starting materials, acetaldehyde and pentanal. Select TWO compounds. H O= H

A: Aldol condensation: Carbonyl compounds having alpha-hydrogen undergo self condensation in the…

Q: Hi, can you help me to draw a mechanism for the formation of an alcohol-containing ring and a…

A: An organic reaction in which enolate ion (which is formed by the reaction of an aldehyde with base…

Q: Show two Robinson annulation products

A: Let us discuss the reaction.

Q: *Pu OK it 90 °C

A: An aldol condensation is a condensation reaction in which an enolate ion reacts with a carbonyl…

Q: 6 C2H5O2C- +2 C2H5O2C- C=O 1) aq. NaHCO3 2) H3O* & heat C12H1602

A:

Q: 2) An enolate attacks an aldehyde and the resulting product is subsequently protonated. type of…

A: Reaction condition given:  An enolate attacks an aldehyde and the resulting product is subsequently…

Q: Draw the structure of the major aldol product (prior to possible dehydration) of the following…

A:

Q: احا anyMS 2:01 +H جمله مش ضد Ha :g OH مطة ا

A: In our mechanism base will abstract acidic protons.  Then after formation of enolate ion i.e inol…

Q: I need a detailed mechanism for the aldol condensation reaction bewtween cyclobutanone and…

A: In this question, we have to find out the correct answer of given problem by the help of the…

Q: The right-hand side of this reaction shows the product of an aldol condensation. What are the…

A: In an aldol condensation reaction, two carbonyl compounds (one of them should have at least one…

Q: OH

A:

Q: which of the following could result from the dehydration of a self-aldol condensation prod (draw…

A: Aldol condensation is self condensation between two aldehyde or tow ketone to form the alpha-beta…

Q: Н онд Н КОН Н КОН -

A: The question is based on organic reactions.     we need to identify the product formed and explain…

Q: Draw the aldol product C6H12O2 from two acetones. Consider the mechanism to predict the product.

A: Aldol reaction: The alpha hydrogen of carbonyl compounds is acidic in nature and it is removed as a…

Q: Write a reaction sequence of 4 steps and, afterwards, write the retrosynthesis

A:

Q: 2. 11 For each of the following aldehydes, draw the aldol product that will result when the aldehyde…

A:

Q: Draw the mechanisms using curved arrows and predict the product for the reactions.

A: When electrophile is added to the conjugated diene, two types of products are possible, kinetic…

Q: 2. draw the mechanism to show how to reduce the ester only 0 -OCH2CH2CH3

A:

Q: CH3OH (large excess) HOTS HN(CH3)2 CH3CO₂H

A: An arrow always depicts from a region of high electron density to low electron density ; that is…

Q: Draw the two carbonyl compounds which could be used to make the enone shown below via the aldol…

A: Applying concept of Aldol reaction.

Q: Show how you could achieve the following transformation. Be sure to show the product produced after…

A:

Q: Draw the enolate anion and the ketone or aldehyde that would be needed to make this product through…

A: Given structure of alpha-beta unsaturated ketone is :  Draw the enolate ion and the ketone or…

Q: H СНЗ А cyclopentyl methyl ketone В Show the mechanism of a crossed aldol reaction starting with…

A:

Q: I believe that this rxn will proceed via Eliminatin but I can't draw the mechanism.

A: Elimination reaction: An elimination reaction is removal of two substituents in a molecule and forms…

Q: need a pushing mechanism for 3,4 dimethoxy-benzaldehyde and 1-indanone in the presence of NaOH. This…

A: First base abstract acidic H+ and nucleophile Attack on benzaldehyde then addition of water gives…

Q: I need help with a retrosynthesis type problem   How do you go from isoamyl alcohol to…

A: Target Molecule=( Propan-2-yl) amine  FGI=functional group interconversion from alcohol to amine…

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.