5. Sickle cell disease is inherited in an autosomal recessive manner. If Josh and Katie each have a sibling with sickle cell disease, but neither Josh nor Katie nor any of their parents have the disease, then what is the chance that a child of Josh and Katie's will have sickle cell disease? (Hint: First determine the chance that Josh and Katie are carriers of the disease.)

5. Sickle cell disease is inherited in an autosomal recessive manner. If Josh and Katie each have a sibling with sickle cell disease, but neither Josh nor Katie nor any of their parents have the disease, then what is the chance that a child of Josh and Katie's will have sickle cell disease? (Hint: First determine the chance that Josh and Katie are carriers of the disease.)

Name: 5. Sickle cell disease is inherited in an autosomal recessive manner.
Uploaded: 2024-03-20T06:43:04.000Z
Channel: Bartleby
Description: 5. Sickle cell disease is inherited in an autosomal recessive manner. If Josh and Katie each have a siblingwith sickle cell disease, but neither Josh nor Katie nor any of their parents have the disease, then what isthe chance that a child of Josh an

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter1: A Perspective On Human Genetics

Section: Chapter Questions

Problem 9QP: If your father were diagnosed with an inherited disease that develops around the age of 50, would...

See similar textbooks

Similar questions

2. STATEMENT: A woman and man both do not have sickle-cell anemia, but both had one parent who had sickle cell. Sickle-cell is an autosomal (somatic) recessive trait. a) What is the genotype for the woman, man and each of their parents? b) This couple unexpectedly is going to have their first child. i. What's the probability that their child will have not have sickle cell like the couple? ii. What's the probability that the child will have sickle cell like one the grandparents?
2. The common grandfather of two first cousins has hereditary hemochromatosis, a recessive condition causing an abnormal buildup of iron in the body. Neither ofthe cousins has the disease nor do any of their relatives.a. If the first cousins had a child, what is the chancethat the child would have hemochromatosis?Assume that the unrelated, unaffected parents ofthe cousins are not carriers.b. How would your calculation change if you knewthat 1 out of every 10 unaffected people in the population (including the unrelated parents of thesecousins) was a carrier for hemochromatosis?
1) Suppose thatt everyone in your family (bloodline) has attached earlobes. Do you know with certainty what your gentype is? a) Your spouse also has attached earlobes, but both your children have unattached earlobes. What is your genotype, and what is your spouse's genotype?
6. A woman and a man, both with normal clotting blood, have a son who has hemophilia. Both of their daughtersare normal. (Note: Assume all possibilities in the children are represented.)a. What pattern of inheritance is this?b. What is the genotypes of the parents?c. If they decide to have another child, what is the chance it will be a boy who has hemophilia? A girl whohas hemophilia?
5. A female child, Della, has the autosomal dominant condition of polydactyly. Della's mother has the normal number of fingers and toes like her parents and brother (Della's maternal grandparents and uncle). Della's father has six fingers on each hand and so did two of his three sisters and his mother (Della's paternal aunt and grandmother). Della has a younger brother who has the normal number of fingers and toes. Give the genotype of each parent and each child. Della's Mother Della's Father Della Della's Brother 5. Draw a pedigree demonstrating polydactyly in the family above. 7
6. Alice has type A blood and her husband Mark has type B blood. Their first child, Amanda, has type O blood. Their second child, Alex, has type AB blood. What is Alice's genotype? What is Mark's genotype?_ Show how you found the answer by completing the Punnett square(s) below: 7. Candace has type B blood. Her husband Dan has type AB blood. Is it possible for Candace and Dan to have a child that has O blood? Explain why or why not (use a Punnett square to help). 8. Ralph has type B blood and his wife Rachel has type A blood. They are very shocked to hear that their baby has type O blood, and think that a switch might have been made at the hospital. Can this baby be theirs? Explain why or why not (use a Punnett square to help).
2
Mary has hemophilia, an X-linked recessive trait. From which of the following individuals could Mary NOT have inherited a hemophilia allele? O Her father O Her father's mother O Her mother's mother O Her father's father O Her mother's father
3) The ability to curl ones’ tongue up on the sides (T) is dominant to not being able to roll your tongue (t). a. A woman who can roll her tongue marries a man who cannot. The first child has the same phenotype as the father, what are the genotypes of the mother, father, and this child? b. What is the probability that the second child won’t be able to roll it’s tongue?
4. Sickle Cell Anemia is an autosomal recessive trait. Given one parent is a carrier and the other parent does not carry the allele , what is the likelihood that their child will haye sickle cell anemia?
1. Mary and Joe are both healthy individuals. Joe has a mother who suffered from cystic fibrosis, an autosomal recessive disorder. Mary has been genetically tested in order to find out if she has the allele responsible for this disease and her tests came out positive. They are planning on having two children together in the near future. What is the probability that she and Joe will have either 2 boys who have the disorder, OR that they have one boy who has the disorder and one boy who does not? (in other words, what is the probability that any of these two outcomes takes place? a) 1/8 b) 1/16 c) 3/32 d) 1/64 e) 9/64
6