← + 5 2 QT ΑΙ 1. SECTION A Answer BOTH questions in this section (Each question is worth 20 marks) Answer ALL parts of this question. (a) Compare the structure of the ß-lactam antibiotic A with antibiotic X shown in Figure Q1(a) in terms of how structural differences affect the following properties; (i) Spectrum of activity. (ii) Resistance to ẞ-Lactamases. (iii) Oral bioavailability. (3 marks) (3 marks) (3 marks) (b) HH H H ΗΝ Ξ S ΗΝ Ξ S CO₂H A CO₂H X Figure Q1(a) The drugs that are available for Highly Active Antiretroviral Therapy (HAART) can be broken down into five classes. Define three of these classes providing one drug example for each. (6 marks) Question 1 continued on page 2....
← + 5 2 QT ΑΙ 1. SECTION A Answer BOTH questions in this section (Each question is worth 20 marks) Answer ALL parts of this question. (a) Compare the structure of the ß-lactam antibiotic A with antibiotic X shown in Figure Q1(a) in terms of how structural differences affect the following properties; (i) Spectrum of activity. (ii) Resistance to ẞ-Lactamases. (iii) Oral bioavailability. (3 marks) (3 marks) (3 marks) (b) HH H H ΗΝ Ξ S ΗΝ Ξ S CO₂H A CO₂H X Figure Q1(a) The drugs that are available for Highly Active Antiretroviral Therapy (HAART) can be broken down into five classes. Define three of these classes providing one drug example for each. (6 marks) Question 1 continued on page 2....
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Question
Transcribed Image Text:← + 5 2
QT
ΑΙ
1.
SECTION A
Answer BOTH questions in this section (Each question is worth 20 marks)
Answer ALL parts of this question.
(a)
Compare the structure of the ß-lactam antibiotic A with antibiotic X
shown in Figure Q1(a) in terms of how structural differences affect the
following properties;
(i) Spectrum of activity.
(ii) Resistance to ẞ-Lactamases.
(iii) Oral bioavailability.
(3 marks)
(3 marks)
(3 marks)
(b)
HH
H H
ΗΝ Ξ
S
ΗΝ Ξ
S
CO₂H
A
CO₂H
X
Figure Q1(a)
The drugs that are available for Highly Active Antiretroviral Therapy
(HAART) can be broken down into five classes. Define three of these
classes providing one drug example for each.
(6 marks)
Question 1 continued on page 2....
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