Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
![4. What are the products obtained from the following elimination reaction? Indicate the major
product.
ÇH3
CH3CH2CCH3
+
H2O
ČI](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F06089eb2-ff0d-4c09-8152-ab59813eefd5%2F39732e9e-f77d-454a-bcfc-a9fc32f009aa%2Fdshy3b0o_processed.jpeg&w=3840&q=75)
![1. For each of the following pairs of SN2 reactions, indicate which reaction occurs faster:
a)
CH;CH2BR + H2O
OR
CH;CH,Br + OH
b) Remember the following is under an SN2 condition:
CH;CH2CHBr +
ČH3
CH3CHCH,Br
OH"
+ OH
OR
ČH3](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F06089eb2-ff0d-4c09-8152-ab59813eefd5%2F39732e9e-f77d-454a-bcfc-a9fc32f009aa%2Ff7sxzmj_processed.jpeg&w=3840&q=75)
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