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4. PI3K is a lipid kinase that acts as a signal transducer. (a) What is the most well-characterized product of the PI3K-catalyzed reaction? (b) Explain why PTEN is classified as a tumor suppressor, being sure to describe its specific catalytic function in your response. PTEN is an inhibitor of PI3K thereby blocks PI3K/AKT/mTORC1 pathway that promotes cell growth.

4. PI3K is a lipid kinase that acts as a signal transducer. (a) What is the most well-characterized product of the PI3K-catalyzed reaction? (b) Explain why PTEN is classified as a tumor suppressor, being sure to describe its specific catalytic function in your response. PTEN is an inhibitor of PI3K thereby blocks PI3K/AKT/mTORC1 pathway that promotes cell growth.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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4. PI3K is a lipid kinase that acts as a signal transducer. (a) What is the most well-characterized product of the PI3K-catalyzed reaction? (b) Explain why PTEN is classified as a tumor suppressor, being sure to describe its specific catalytic function in your response. PTEN is an inhibitor of PI3K thereby blocks PI3K/AKT/MTORC1 pathway that promotes cell growth. O Focus prds LE English (United States)
Transcribed Image Text:4. PI3K is a lipid kinase that acts as a signal transducer. (a) What is the most well-characterized product of the PI3K-catalyzed reaction? (b) Explain why PTEN is classified as a tumor suppressor, being sure to describe its specific catalytic function in your response. PTEN is an inhibitor of PI3K thereby blocks PI3K/AKT/MTORC1 pathway that promotes cell growth. O Focus prds LE English (United States)
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