4. PI3K is a lipid kinase that acts as a signal transducer. (a) What is the most well-characterized product of the PI3K-catalyzed reaction? (b) Explain why PTEN is classified as a tumor suppressor, being sure to describe its specific catalytic function in your response. PTEN is an inhibitor of PI3K thereby blocks PI3K/AKT/mTORC1 pathway that promotes cell growth.
4. PI3K is a lipid kinase that acts as a signal transducer. (a) What is the most well-characterized product of the PI3K-catalyzed reaction? (b) Explain why PTEN is classified as a tumor suppressor, being sure to describe its specific catalytic function in your response. PTEN is an inhibitor of PI3K thereby blocks PI3K/AKT/mTORC1 pathway that promotes cell growth.
Biology 2e
2nd Edition
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter9: Cell Communication
Section: Chapter Questions
Problem 1VCQ: Figure 9.8 HER2 is a receptor tyrosine kinase. In 30 percent of human breast cancers, HER2 is...
Related questions
Question
100%
Do you know #4 ?
![4. PI3K is a lipid kinase that acts as a signal transducer.
(a) What is the most well-characterized product of the PI3K-catalyzed reaction?
(b) Explain why PTEN is classified as a tumor suppressor, being sure to describe its specific
catalytic function in your response.
PTEN is an inhibitor of PI3K thereby blocks PI3K/AKT/MTORC1 pathway that promotes cell
growth.
O Focus
prds
LE
English (United States)](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fe7ec106d-cdb6-462d-82f1-cffdbc407fec%2Fff96bae8-58fa-407d-9af8-fc488952a7fe%2Flbq32v_processed.jpeg&w=3840&q=75)
Transcribed Image Text:4. PI3K is a lipid kinase that acts as a signal transducer.
(a) What is the most well-characterized product of the PI3K-catalyzed reaction?
(b) Explain why PTEN is classified as a tumor suppressor, being sure to describe its specific
catalytic function in your response.
PTEN is an inhibitor of PI3K thereby blocks PI3K/AKT/MTORC1 pathway that promotes cell
growth.
O Focus
prds
LE
English (United States)
Expert Solution
![](/static/compass_v2/shared-icons/check-mark.png)
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution!
Trending now
This is a popular solution!
Step by step
Solved in 3 steps
![Blurred answer](/static/compass_v2/solution-images/blurred-answer.jpg)
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Recommended textbooks for you
![Biology 2e](https://www.bartleby.com/isbn_cover_images/9781947172517/9781947172517_coverImage_Textbooks.gif)
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
![Biology (MindTap Course List)](https://www.bartleby.com/isbn_cover_images/9781337392938/9781337392938_smallCoverImage.gif)
Biology (MindTap Course List)
Biology
ISBN:
9781337392938
Author:
Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:
Cengage Learning
![Biology 2e](https://www.bartleby.com/isbn_cover_images/9781947172517/9781947172517_coverImage_Textbooks.gif)
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
![Biology (MindTap Course List)](https://www.bartleby.com/isbn_cover_images/9781337392938/9781337392938_smallCoverImage.gif)
Biology (MindTap Course List)
Biology
ISBN:
9781337392938
Author:
Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:
Cengage Learning