Please help me answer numbers 4-5 thank you! V. Questions:1. What are some of the medical applications of karyotyping?2 What kind of chromosomal aberration is exhibited by individuals with cri-du-chatsyndrome? Down syndrome?3. What are other types of chromosomal aberrations? List examples for each type.4. For a couple, what is the significance of knowing chromosomal aberrations?*. What environmental factors may increase incidence of chromosomalabnormalities? Name at least three.

Chromosomal aberrations are the abnormalities in the chromosome. These changes may occur due to the…

Answered: 4. For a couple, what is the…

4. For a couple, what is the significance of knowing chromosomal aberrations? 0. What environmental factors may increase incidence of chromosomal abnormalities? Name at least three.

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter16: Human Genetics And The Human Genome

Section16.3: Genetic Diseases Caused By Single-gene Mutations

Problem 7LO: State whether each of the following genetic defects is inherited as an autosomal recessive,...

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1. What role does a patient's genetics have in their symptoms of muscular dystrophy? What causes various mutations to cause distinct symptoms? (two to three sentences) (Think about why various mutations in different genes cause different illnesses.)2. What can family history teach you about a patient's muscular dystrophy inheritance and, hence, genetic basis? (two to three sentences)3. The X-chromosome contains the mutation that causes Duchenne Muscular Dystrophy (DMD). Explains how this impacts DMD inheritance and why DMD patients are disproportionately male. (two to three sentences)
b. The following diagram shows a family tree of individuals with haemophilia. B i. Based on an X-linked recessive pattern of inheritance, work out the likely genotypes of the individuals indicated by the letters. Individual A Individual B Individual C GENOTYPE ii. If individual C has children with a normal male, what are the chances that they will have haemophilia? Explain your answer fully. iii. If individual C has children with a normal male, what are the chances that their daughters will be carriers of the condition? Explain your answer fully.
State whether each of the following genetic defects is inherited as an autosomal recessive, autosomal dominant, or X-linked recessive trait: phenylketonuria (PKU), sickle cell anemia, cystic fibrosis, Tay-Sachs disease, Huntingtons disease, and hemophilia A.
2. Imagine that you are in your late 30s or early 40s and decide that you want a child. You realize that you’re at greater risk of having a child with Down’s Syndrome. What sorts of genetic screening are available today? If you find out that this child has this condition, do you think it’s appropriate to have an abortion? Why or why not? Question: Does elective abortion of fetuses with physical or other developmental disabilities have an effect on the perception of personhood, dignity, and rights in society? Explain.
3. D. A. B. C. 10. Familial hypercholesterolemia is the most common genetic cause of heart disease. It is caused by a dominant factor (C). The recessive factor (c) produces a protein that processes cholesterol normally and leads to a normal risk for heart disease. Answer the following questions about the inheritance of this disease. What is the phenotype of a woman whose genotype is Cc? What is the genotype of a man who has hypercholesterolemia but whose mother did not have the disease? If a man who is heterozygous for the disease marries a woman who is heterozygous for the disease, what is the chance that any child of theirs will inherit the disease? If a man who is homozygous dominant marries a woman who is homozygous recessive, what would you predict for the the genotypes and phenotypes of their children? If the first 2 children from the marriage described in D above have the disease, what is the chance that a third child would be normal? Explain your answer. 41
A2.Q what diagnosis would you give patient A? I want to make sure if I'm right and if I'm wrong where did I mess up I said trisomy 13 syndrome
II. Write TRUE if the statement is correct and FALSE if otherwise. -7. A temale parent possessing an X-linked dominant mutation is considered a carrier and will not manifest clinical symptoms of the disorder. _8. Y-linked traits are passed from the father to son, without the occurrence of genetic recombination. 9. Somatic mosaicism results to abnormalities based on the amount and distribution of normal cells while gonadal mosaicism affects the germline tissues leading to a new dominant mutation. 10. A test cross is done to determine which allele is dominant and which is recessive.
E. D. A. B. 11. C. Huntington's disease is a degenerative disease of the nervous system that strikes in middle age. The allele that causes the disease (H) is dominant to the allele that results in the normal condition (h). Answer the following questions about the inheritance of this disease. What is the genotype of a man who is normal but whose father had Huntington's disease? What is the genotype of a woman who has Huntington's disease if both of her parents had Huntington's disease? If a man who is heterozygous for Huntington's disease marries a woman who is normal, what would you expect for the genotypes and phenotypes of their children? If a normal man marries a woman who is homozygous for Huntington's disease, what do you expect for the genotypes and phenotypes of their children? Since Huntington's disease is caused by a dominant allele, does this mean it's also the most common allele in the population? F. Since Huntington's disease is caused by a dominant allele, does this mean…
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2. STATEMENT: A woman and man both do not have sickle-cell anemia, but both had one parent who had sickle cell. Sickle-cell is an autosomal (somatic) recessive trait. a) What is the genotype for the woman, man and each of their parents? b) This couple unexpectedly is going to have their first child. i. What's the probability that their child will have not have sickle cell like the couple? ii. What's the probability that the child will have sickle cell like one the grandparents?
1. What is the genotype of individual #2? Explain how you can tell 2. What is the genotype of individual #3 Explain how you can tell.