4.- Determine the structural relationship between the compounds in each of the pairs that follow. They may be unrelated, identical (the same compound), constitutional isomers, diastereoisomers, enantiomers? - Identify the optically active (chiral) compounds and any meso compounds. - Assign a configuration (R or S) to all stereocenters. - Name all compounds so that the name reflects the structure unambiguously. a) b) c) CHO H- -NH₂ H- HO- -H CH₂OH H CH3 IQ H CH3 CI Ph H CH₂OH -OH HNH2 CHO H3C H I I Ph & I J. CI CH3
4.- Determine the structural relationship between the compounds in each of the pairs that follow. They may be unrelated, identical (the same compound), constitutional isomers, diastereoisomers, enantiomers? - Identify the optically active (chiral) compounds and any meso compounds. - Assign a configuration (R or S) to all stereocenters. - Name all compounds so that the name reflects the structure unambiguously. a) b) c) CHO H- -NH₂ H- HO- -H CH₂OH H CH3 IQ H CH3 CI Ph H CH₂OH -OH HNH2 CHO H3C H I I Ph & I J. CI CH3
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:**Exercise: Structural Relationships of Compounds**
**Instructions:**
For each of the following compound pairs, determine their structural relationship. They may be unrelated, identical (same compound), constitutional isomers, diastereoisomers, or enantiomers.
- Identify the optically active (chiral) compounds and any meso compounds.
- Assign a configuration (R or S) to all stereocenters.
- Name all compounds to clearly reflect their structure.
---
**Compound Pairs:**
**a)**
- **Compound 1:** Features an aldehyde group (CHO), hydroxyl groups (CH2OH), and an amino group (NH2) attached to a carbon chain.
- **Compound 2:** Similar structure to compound 1 but mirrored.
**b)**
- **Compound 1:** Cyclohexane ring with a hydrogen (H) and methyl group (CH3) in specific positions.
- **Compound 2:** Similar to compound 1 but with mirrored positioning of groups.
**c)**
- **Compound 1:** Cyclohexyl structure with phenyl (Ph), chlorine (Cl), hydrogen (H), and a methyl group (CH3).
- **Compound 2:** Configuration mirrored from compound 1.
**d)**
- **Compound 1:** Cyclopropane with carbonyl (C=O) and chlorine (Cl).
- **Compound 2:** Potentially different spatial arrangement compared to compound 1.
**e)**
- **Compound 1:** A six-membered ring with a hydroxyl group (OH), carbonyl, and methyl group (CH3).
- **Compound 2:** A five-membered ester with two methoxy groups (O-CH3).
**f)**
- **Compound 1:** Open chain form of a sugar with hydroxyl (OH) and methyl (CH3) groups.
- **Compound 2:** Closed ring sugar structure (pyranose form) with similar substituents as compound 1.
---
**Notes for Analysis:**
- Consider mirrored configurations for enantiomers.
- Note identical configurations for meso compounds.
- Use CIP (Cahn-Ingold-Prelog) rules for assigning R/S configurations.
- Ensure names reflect stereochemistry accurately.
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