3a. At right is a hypothetical enzyme that breaks down isoleucine (the amino acid substrate is shown bound in the active site). Identify the specificity residues shown and describe the types of interactions the enzyme uses to select isoleucine as a substrate. b. Give at least two reasons why this enzyme would be less active at very high or very low pH. C-CH HNH, CH₂ H-O 1.0 OC-CH₂- enzyme

Chemistry for Today: General, Organic, and Biochemistry
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Chapter20: Enzymes
Section: Chapter Questions
Problem 20.51E
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3a. At right is a hypothetical enzyme that breaks down isoleucine (the amino acid substrate is shown bound
in the active site). Identify the specificity residues shown and
describe the types of interactions the enzyme uses to select
isoleucine as a substrate.
b. Give at least two reasons why this enzyme would be less active
at very high or very low pH.
0 0 H-0
F
CH₂-
H₂C
NCH;C–CH
1.
HNH,
OC-CH₂-
enzyme
Transcribed Image Text:3a. At right is a hypothetical enzyme that breaks down isoleucine (the amino acid substrate is shown bound in the active site). Identify the specificity residues shown and describe the types of interactions the enzyme uses to select isoleucine as a substrate. b. Give at least two reasons why this enzyme would be less active at very high or very low pH. 0 0 H-0 F CH₂- H₂C NCH;C–CH 1. HNH, OC-CH₂- enzyme
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