2. The following mechanism has been proposed for superoxide dismutase. active site H*. H2O2 (ii) H20 H* O2 a. Explain each step in the catalytic cycle. b. What is the net reaction that occurs at this enzyme? c. Fe and Mn SOD’s exist in nature. What is the structure of each? How do thei mechanisms differ from Cu2Zn2SOD?

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2. The following mechanism has been proposed for superoxide dismutase.
active site
H*.
H202
H20
(ii)
H20
N-Zn
H*
O2
a. Explain each step in the catalytic cycle.
b. What is the net reaction that occurs at this enzyme?
c. Fe and Mn SOD’s exist in nature. What is the structure of each? How do their
mechanisms differ from CuzZn2SOD?
Transcribed Image Text:2. The following mechanism has been proposed for superoxide dismutase. active site H*. H202 H20 (ii) H20 N-Zn H* O2 a. Explain each step in the catalytic cycle. b. What is the net reaction that occurs at this enzyme? c. Fe and Mn SOD’s exist in nature. What is the structure of each? How do their mechanisms differ from CuzZn2SOD?
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