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33. How does E. coli distinguish between the old and new strand for mi o longer helicase: ir target at contro Loading ent in the tion, bui clamp c Sliding clamp the slid e is not y factor all inte hus, sl nes tha Su. How do human cells distinguish between the old and new strand for mismatch repair? 37. What are the steps of base excision repair? Where does the glycosylase cleave? 38. Why does the OxoG failsafe system lead to more ATeD CG than CGeDAT transversions? 39. What are the steps of nucleotide excision repair in bacteria? Why are the bacteriál proteins in this pathwar named "UV"ánd human proteins "XP"? 40. Which repair system is tightly coupled to transcription? Why is it important to repair damage sensed by RNA polymerase quickly? 41. What is translesion DNA synthesis and when is it used? Why is it a last resort? Does it repair SSDNA or dsDNA? 42. What are the steps of homologous recombination repair? Which proteins are involved in searching for homologous sequences and how do they function? NTHE 43. What are the steps of nonhomologous end joining? licati usly. sent i brok diffie of th 44. When is NHEJ used as a mechanism for DNA repair? Why is it a last resort? Does it repair SSDNA or dsE 45. Describe the general steps needed for a cell to become cancerous. Thi 46. How do mutations and chromosomal abnormalities affect proteins and lead to disease? 47. What role do cell cycle checkpoints have in cancer? 48. Define a tumor suppressor and oncogepe and give an example of each. 49. Define the role of ATM in the cell and cancer. Upon DNA damage, ATM decideş whether to activat NHEJ. Which is preferred and why? wnigh

33. How does E. coli distinguish between the old and new strand for mi o longer helicase: ir target at contro Loading ent in the tion, bui clamp c Sliding clamp the slid e is not y factor all inte hus, sl nes tha Su. How do human cells distinguish between the old and new strand for mismatch repair? 37. What are the steps of base excision repair? Where does the glycosylase cleave? 38. Why does the OxoG failsafe system lead to more ATeD CG than CGeDAT transversions? 39. What are the steps of nucleotide excision repair in bacteria? Why are the bacteriál proteins in this pathwar named "UV"ánd human proteins "XP"? 40. Which repair system is tightly coupled to transcription? Why is it important to repair damage sensed by RNA polymerase quickly? 41. What is translesion DNA synthesis and when is it used? Why is it a last resort? Does it repair SSDNA or dsDNA? 42. What are the steps of homologous recombination repair? Which proteins are involved in searching for homologous sequences and how do they function? NTHE 43. What are the steps of nonhomologous end joining? licati usly. sent i brok diffie of th 44. When is NHEJ used as a mechanism for DNA repair? Why is it a last resort? Does it repair SSDNA or dsE 45. Describe the general steps needed for a cell to become cancerous. Thi 46. How do mutations and chromosomal abnormalities affect proteins and lead to disease? 47. What role do cell cycle checkpoints have in cancer? 48. Define a tumor suppressor and oncogepe and give an example of each. 49. Define the role of ATM in the cell and cancer. Upon DNA damage, ATM decideş whether to activat NHEJ. Which is preferred and why? wnigh

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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33. How does E. coli distinguish between the old and new strand for mi o longer helicase: ir target at contro Loading ent in the tion, bui clamp c Sliding clamp the slid e is not y factor all inte hus, sl nes tha Su. How do human cells distinguish between the old and new strand for mismatch repair? 37. What are the steps of base excision repair? Where does the glycosylase cleave? 38. Why does the OxoG failsafe system lead to more ATeD CG than CGeDAT transversions? 39. What are the steps of nucleotide excision repair in bacteria? Why are the bacteriál proteins in this pathwar named "UV"ánd human proteins "XP"? 40. Which repair system is tightly coupled to transcription? Why is it important to repair damage sensed by RNA polymerase quickly? 41. What is translesion DNA synthesis and when is it used? Why is it a last resort? Does it repair SSDNA or dsDNA? 42. What are the steps of homologous recombination repair? Which proteins are involved in searching for homologous sequences and how do they function? NTHE 43. What are the steps of nonhomologous end joining? licati usly. sent i brok diffie of th 44. When is NHEJ used as a mechanism for DNA repair? Why is it a last resort? Does it repair SSDNA or dsE 45. Describe the general steps needed for a cell to become cancerous. Thi 46. How do mutations and chromosomal abnormalities affect proteins and lead to disease? 47. What role do cell cycle checkpoints have in cancer? 48. Define a tumor suppressor and oncogepe and give an example of each. 49. Define the role of ATM in the cell and cancer. Upon DNA damage, ATM decideş whether to activat NHEJ. Which is preferred and why? wnigh
Transcribed Image Text:33. How does E. coli distinguish between the old and new strand for mi o longer helicase: ir target at contro Loading ent in the tion, bui clamp c Sliding clamp the slid e is not y factor all inte hus, sl nes tha Su. How do human cells distinguish between the old and new strand for mismatch repair? 37. What are the steps of base excision repair? Where does the glycosylase cleave? 38. Why does the OxoG failsafe system lead to more ATeD CG than CGeDAT transversions? 39. What are the steps of nucleotide excision repair in bacteria? Why are the bacteriál proteins in this pathwar named "UV"ánd human proteins "XP"? 40. Which repair system is tightly coupled to transcription? Why is it important to repair damage sensed by RNA polymerase quickly? 41. What is translesion DNA synthesis and when is it used? Why is it a last resort? Does it repair SSDNA or dsDNA? 42. What are the steps of homologous recombination repair? Which proteins are involved in searching for homologous sequences and how do they function? NTHE 43. What are the steps of nonhomologous end joining? licati usly. sent i brok diffie of th 44. When is NHEJ used as a mechanism for DNA repair? Why is it a last resort? Does it repair SSDNA or dsE 45. Describe the general steps needed for a cell to become cancerous. Thi 46. How do mutations and chromosomal abnormalities affect proteins and lead to disease? 47. What role do cell cycle checkpoints have in cancer? 48. Define a tumor suppressor and oncogepe and give an example of each. 49. Define the role of ATM in the cell and cancer. Upon DNA damage, ATM decideş whether to activat NHEJ. Which is preferred and why? wnigh
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