3..° i We seem to be constantly chasing the latest great oil to use for cooking and currently avocado oil seems to be one of the favorites. Avocado oil contains oleic acid (18:149) as its primary unsaturated fatty acid. Unfortunately, several brands of avocado oil are adulterated with other oils, usually soybean oil (several brands of "avocado" oil are almost 100% soybean oil and generally have a price that is at least half that of other brands) so beware of what you are buying. Consider a situation where two molecules of oleic acid were used for the production of ß-hydroxybutyrate through the processes of ß-oxidation followed by the reaction seen below. Note that if this reaction is active, the acetyl CoA does not enter the citric acid cycle. 2 COA COA NADH NAD+ H+ OH B-hydroxybutyrate a) What are the ß-oxidation products of two molecules of oleic acid? How much ATP is required? b) How many molecules of ß-hydroxybutyrate can be produced from two molecules of oleic acid? How many NADH are required? c) Using the net production of NADH and FADH₂ from above, what is the typical ATP yield from two molecules of oleic acid being converted into ß-hydroxybutyrate?
3..° i We seem to be constantly chasing the latest great oil to use for cooking and currently avocado oil seems to be one of the favorites. Avocado oil contains oleic acid (18:149) as its primary unsaturated fatty acid. Unfortunately, several brands of avocado oil are adulterated with other oils, usually soybean oil (several brands of "avocado" oil are almost 100% soybean oil and generally have a price that is at least half that of other brands) so beware of what you are buying. Consider a situation where two molecules of oleic acid were used for the production of ß-hydroxybutyrate through the processes of ß-oxidation followed by the reaction seen below. Note that if this reaction is active, the acetyl CoA does not enter the citric acid cycle. 2 COA COA NADH NAD+ H+ OH B-hydroxybutyrate a) What are the ß-oxidation products of two molecules of oleic acid? How much ATP is required? b) How many molecules of ß-hydroxybutyrate can be produced from two molecules of oleic acid? How many NADH are required? c) Using the net production of NADH and FADH₂ from above, what is the typical ATP yield from two molecules of oleic acid being converted into ß-hydroxybutyrate?
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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Transcribed Image Text:3..° i
We seem to be constantly chasing the latest great oil to use for cooking and
currently avocado oil seems to be one of the favorites. Avocado oil contains oleic acid (18:149)
as its primary unsaturated fatty acid. Unfortunately, several brands of avocado oil are
adulterated with other oils, usually soybean oil (several brands of "avocado" oil are almost 100%
soybean oil and generally have a price that is at least half that of other brands) so beware of
what you are buying. Consider a situation where two molecules of oleic acid were used for the
production of ß-hydroxybutyrate through the processes of ß-oxidation followed by the reaction
seen below. Note that if this reaction is active, the acetyl CoA does not enter the citric acid
cycle.
2
COA
CoA
O
NADH NAD+
H+
OH
B-hydroxybutyrate
a) What are the ß-oxidation products of two molecules of oleic acid? How much ATP is
required?
O
b) How many molecules of ß-hydroxybutyrate can be produced from two molecules of oleic
acid? How many NADH are required?
c) Using the net production of NADH and FADH₂ from above, what is the typical ATP yield
from two molecules of oleic acid being converted into ß-hydroxybutyrate?
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