3. In the early days of studies of the mechanism of the hydroxide ion-promoted hydrolysis of ester, it was labeled as shown below, which of the products would contain the 180 label if (a) the acyl C-O bond is not clear which bond was broken-the acyl C-O bond or the alkyl C-O bond. Using ethyl benzoate broken and (b) the alkyl C-O bond is broken? D osnou kynbos bus animosi 1923 to 2292 NaOH 18 anivollot H₂O bat ob

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Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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3. In the early days of studies of the mechanism of the hydroxide ion-promoted hydrolysis of ester, it was
labeled as shown below, which of the products would contain the 180 label if (a) the acyl C-O bond is
not clear which bond was broken-the acyl C-O bond or the alkyl C-O bond. Using ethyl benzoate
broken and (b) the alkyl C-O bond is broken? amig
to 2129diny2
of
b. an SN2 reaction:
c. an SN1 reaction:
motl'sigin
4. Suppose it is possible to propose the OH--catalyzed hydrolysis of ester as occurring by one of the follow-
ing mechanisms:
a. nucleophilic acyl reaction:
bowalls
boiadei ori blaow abnuogr
lonaitiem balsdr
OR
9257
HO:
1823
HO:
7.-
:Ö:
bbs olosried
+ NaOH
-OR
OH
08:0:
:0:
O: +
O: + R
H₂O
ROH
420 HO
:O:
oy wheslo fork witblad runiqxs
+ ROH
have an ines
ROH
Develop an experiment that would distinguish these three mechanisms/reactions from one another.
Transcribed Image Text:3. In the early days of studies of the mechanism of the hydroxide ion-promoted hydrolysis of ester, it was labeled as shown below, which of the products would contain the 180 label if (a) the acyl C-O bond is not clear which bond was broken-the acyl C-O bond or the alkyl C-O bond. Using ethyl benzoate broken and (b) the alkyl C-O bond is broken? amig to 2129diny2 of b. an SN2 reaction: c. an SN1 reaction: motl'sigin 4. Suppose it is possible to propose the OH--catalyzed hydrolysis of ester as occurring by one of the follow- ing mechanisms: a. nucleophilic acyl reaction: bowalls boiadei ori blaow abnuogr lonaitiem balsdr OR 9257 HO: 1823 HO: 7.- :Ö: bbs olosried + NaOH -OR OH 08:0: :0: O: + O: + R H₂O ROH 420 HO :O: oy wheslo fork witblad runiqxs + ROH have an ines ROH Develop an experiment that would distinguish these three mechanisms/reactions from one another.
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