3. In a study of the adverse effects of x-rays among children, a retrospective cohort study was done using records from several large children's hospitals for the period of 1980 to 1985. 10,000 children were selected as a representative population of ill children seen at the hospitals during that time. Subjects were classified according to whether or not they received an x-ray during their stay in the hospital and were followed from their hospital stay through 2005 for the development of cancer. During the follow-up period, 49 incident cancers occurred in 3,263 children who had received an x-ray, and 47 incident cancers occurred in the 6,737 children who had not received an x-ray during their hospitalization. What is the attributable risk of cancer due to x-ray in this study population? What is the interpretation of this estimate?

MATLAB: An Introduction with Applications
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**Study on the Adverse Effects of X-rays Among Children**

In this research, a retrospective cohort study was conducted to examine the adverse effects of x-rays on children. Data from several large children's hospitals, spanning the years 1980 to 1985, were utilized. A total of 10,000 children were selected to represent a population of ill children treated at these hospitals during that timeframe.

**Methodology:**
The children were divided into groups based on whether they had received an x-ray during their hospital stay. They were monitored from the time of hospitalization until 2005 to assess the development of cancer.

**Findings:**
- Among 3,263 children who had received an x-ray, there were 49 cases of cancer.
- Among 6,737 children who had not received an x-ray, there were 47 cases of cancer.

**Discussion Points:**
- **Attributable Risk of Cancer Due to X-rays:** The study seeks to determine the attributable risk of cancer associated with x-ray exposure in this population.
- **Interpretation of Estimate:** Understanding how x-ray exposure potentially correlates with increased cancer risk helps inform medical guidelines and safety protocols for pediatric care. 

This study highlights the importance of analyzing long-term health outcomes following medical procedures like x-rays among vulnerable populations such as children.
Transcribed Image Text:**Study on the Adverse Effects of X-rays Among Children** In this research, a retrospective cohort study was conducted to examine the adverse effects of x-rays on children. Data from several large children's hospitals, spanning the years 1980 to 1985, were utilized. A total of 10,000 children were selected to represent a population of ill children treated at these hospitals during that timeframe. **Methodology:** The children were divided into groups based on whether they had received an x-ray during their hospital stay. They were monitored from the time of hospitalization until 2005 to assess the development of cancer. **Findings:** - Among 3,263 children who had received an x-ray, there were 49 cases of cancer. - Among 6,737 children who had not received an x-ray, there were 47 cases of cancer. **Discussion Points:** - **Attributable Risk of Cancer Due to X-rays:** The study seeks to determine the attributable risk of cancer associated with x-ray exposure in this population. - **Interpretation of Estimate:** Understanding how x-ray exposure potentially correlates with increased cancer risk helps inform medical guidelines and safety protocols for pediatric care. This study highlights the importance of analyzing long-term health outcomes following medical procedures like x-rays among vulnerable populations such as children.
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From the provided information, the following are interpreted:

For children, who received an x-ray:Total no. of children=3263No. of children, whod eveloped cancer=47For children, who did not received an x-ray:Total no. of children=6737No. of children, who developed cancer=47

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