3. Glycine is a diprotic acid that can undergo two dissociation reactions, one for the a-amino group and the other for the carboxyl group. Therefore, it has two pKa values. The carboxyl group has a pKa1 of 2.34 and the a-amino group has a pKa2 of 9.60. Glycine can exist in fully deprotonated, fully protonated or zwitterionic form. H H H H H H H ΝΘ он он H C-H H- -H H-C-H H -H ion at low pH zwitterion neutral pH 天 ion at high pH Determine the concentrations of glycine's different protonated forms at a. pH 2.0 b. pH 5.0 c. pH 12.0

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Chapter22: Organic And Biological Molecules
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3. Glycine is a diprotic acid that can undergo two dissociation reactions, one for the a-amino group and
the other for the carboxyl group. Therefore, it has two pKa values. The carboxyl group has a pKa1 of
2.34 and the a-amino group has a pKa2 of 9.60. Glycine can exist in fully deprotonated, fully protonated
or zwitterionic form.
H
H
H
H
H
H
H
ΝΘ
он
он
H
C-H
H-
-H
H-C-H
H
-H
ion at low pH
zwitterion
neutral pH
天
ion at high pH
Determine the concentrations of glycine's different protonated forms at
a. pH 2.0
b. pH 5.0
c. pH 12.0
Transcribed Image Text:3. Glycine is a diprotic acid that can undergo two dissociation reactions, one for the a-amino group and the other for the carboxyl group. Therefore, it has two pKa values. The carboxyl group has a pKa1 of 2.34 and the a-amino group has a pKa2 of 9.60. Glycine can exist in fully deprotonated, fully protonated or zwitterionic form. H H H H H H H ΝΘ он он H C-H H- -H H-C-H H -H ion at low pH zwitterion neutral pH 天 ion at high pH Determine the concentrations of glycine's different protonated forms at a. pH 2.0 b. pH 5.0 c. pH 12.0
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