3. Feedback inhibition can regulate enzyme catalyzed pathways A. Describe the feedback that is occurring in the diagram below and EXPLAIN its importance 1st intermediate substrate 2nd intermediate substrate End product Substrate Enzyme 1 Enzyme 2 Enzyme 3 Inhibition of process B. Identify the structure that is acting as the allosteric regulator in the above feedback

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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3. Feedback inhibition can regulate enzyme catalyzed pathways
A. Describe the feedback that is occurring in the diagram below and EXPLAIN its
importance
1st intermediate
2nd intermediate
substrate
substrate
End
product
Substrate
Enzyme 1
Enzyme 2
Enzyme 3
Inhibition of process
B. Identify the structure that is acting as the allosteric regulator in the above feedback
Transcribed Image Text:3. Feedback inhibition can regulate enzyme catalyzed pathways A. Describe the feedback that is occurring in the diagram below and EXPLAIN its importance 1st intermediate 2nd intermediate substrate substrate End product Substrate Enzyme 1 Enzyme 2 Enzyme 3 Inhibition of process B. Identify the structure that is acting as the allosteric regulator in the above feedback
Stimulates glucose
uptake by cells
Tissue cells
Insulin
Stimulates
glycogen
formation
F. For the negative feedback example answer the
following:
Describe a mutation that could occur
Glucose
Glycogen
Pancreas
Blood
Liver
glucose
falls to
normal
range.
IMBALANCE
Stimulus
t Blood
glucose level
BALANCE: Normal blood glucose level (about 90 mg/100 ml)
Predict the impact the mutation would have
on the negative feedback loop
Stimulus
| Blood
glucose level
IMBALANCE
Blood
glucose
rises to
normal
range.
Pancreas
Justify your prediction
Glucose Glycogen
Liver
Stimulates
glycogen
breakdown
Glucagon
0 2013 Pearson Education, Inc.
Transcribed Image Text:Stimulates glucose uptake by cells Tissue cells Insulin Stimulates glycogen formation F. For the negative feedback example answer the following: Describe a mutation that could occur Glucose Glycogen Pancreas Blood Liver glucose falls to normal range. IMBALANCE Stimulus t Blood glucose level BALANCE: Normal blood glucose level (about 90 mg/100 ml) Predict the impact the mutation would have on the negative feedback loop Stimulus | Blood glucose level IMBALANCE Blood glucose rises to normal range. Pancreas Justify your prediction Glucose Glycogen Liver Stimulates glycogen breakdown Glucagon 0 2013 Pearson Education, Inc.
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