3. 1,2-Diphenyl-1-propanol can be prepared by hydride reduction of 1,2- diphenyl-1-proanone or by addition of phenylmagnesium bromide to 2- phenylpropanal. Use the Felkin-Ahn model to predict the stereochemistry of the major product for each reaction. Assume aqueous work up to achieve neutral products. OH a. b. Ph. Ph Ph CH3 1,2-diphenyl-1-propanone H CH3 2-phenylpropanal NaBH4 PhMgBr Ph. Ph. CH3 1,2-Diphenyl-1-propanol OH Ph Ph CH3 1,2-Diphenyl-1-propanol 1

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3.
1,2-Diphenyl-1-propanol can be prepared by hydride reduction of 1,2-
diphenyl-1-proanone or by addition of phenylmagnesium bromide to 2-
phenylpropanal. Use the Felkin-Ahn model to predict the stereochemistry of the
major product for each reaction. Assume aqueous work up to achieve neutral
products.
OH
a.
b.
Ph.
Ph
Ph
CH3
1,2-diphenyl-1-propanone
NaBH4
H
CH3
2-phenylpropanal
PhMgBr
Ph.
Ph.
CH3
1,2-Diphenyl-1-propanol
OH
Ph
Ph
CH3
1,2-Diphenyl-1-propanol
1
Transcribed Image Text:3. 1,2-Diphenyl-1-propanol can be prepared by hydride reduction of 1,2- diphenyl-1-proanone or by addition of phenylmagnesium bromide to 2- phenylpropanal. Use the Felkin-Ahn model to predict the stereochemistry of the major product for each reaction. Assume aqueous work up to achieve neutral products. OH a. b. Ph. Ph Ph CH3 1,2-diphenyl-1-propanone NaBH4 H CH3 2-phenylpropanal PhMgBr Ph. Ph. CH3 1,2-Diphenyl-1-propanol OH Ph Ph CH3 1,2-Diphenyl-1-propanol 1
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