2. When the following pair of reactants are combined in the presence of a basic catalyst, a number of aldol addition products are possible (since both of the reactants possess an acidic alpha proton). a. b. C. CH3 + H₂C H NaOH/H₂O Draw the structures for the two possible enolate ions. Draw the structures for all possible aldol addition products (also show the enolate ion and electrophilic carbonyl compound responsible for each product). For each of the aldol addition products predicted in part b, draw the structures for all of the corresponding aldol condensation products after loss of water (if E/Z isomers are possible, show both isomers)

2. When the following pair of reactants are combined in the presence of a basic catalyst, a number of aldol addition products are possible (since both of the reactants possess an acidic alpha proton). a. b. C. CH3 + H₂C H NaOH/H₂O Draw the structures for the two possible enolate ions. Draw the structures for all possible aldol addition products (also show the enolate ion and electrophilic carbonyl compound responsible for each product). For each of the aldol addition products predicted in part b, draw the structures for all of the corresponding aldol condensation products after loss of water (if E/Z isomers are possible, show both isomers)

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Similar questions

The enolate derived from diethyl malonate reacts with a variety of electrophiles (not just alkyl halides) to form new carbon–carbon bonds. With this in mind, draw the products formed when Na+ −CH(CO2Et)2 reacts with each electrophile, followed by treatment with H2O.
4. In the following compound: (a). Circle the good leaving group. (b). Explain why it is a good leaving group. HO,
Convert each compound to its enol or keto tautomer. -OH i asdas CH3 CH3 Draw the aldol product formed from each compound. CH,CHO a. a. a. CHO b. Which carbonyl compounds do not undergo an aldol reaction when treated with "OH in H₂O? ol b. b. (CH3)3CCH,CHO oor & C. d. CH3 CH3 C. į d. (CH3)3C H (CH3)3C CH3 Draw the products formed in each crossed aldol reaction. a. CH3CH,CH,CHO and CH2=O c. CH₂CHO and b. CH₂COCH, and CH₂=O e. CHO
6. The synthesis of alpha enol derivatives is important since these compounds with appropriate substituents in the correct positions can have desired biological effects, which is why the study of obtaining these compounds is important. Thus, a reaction from alpha-ketones with a lithium derivative is studied. a. Indicate the reaction intermediate and product. b. Perform the reaction mechanism. Eter H20 Intermediate Product
4.Which is the most thermodynamically stable product of the following aldol condensation reaction? NaOH H. Me `Me EtOH а. Е, Z b. Е, E с. Z, E d. Z,Z