2. When the following Negishi cross-coupling reaction was attempted, two different products were observed. (A) Draw a plausible catalytic cycle that explains the formation of the desired product. Label all mechanistic sticks. [Pd] can be used as the active catalyst. (B) Suggest how the undesired side-product may have formed. Hint: alkyl-Pd species are not particularly stable. Br ZnCl [Pd] catalyst desired product undesired side-product
2. When the following Negishi cross-coupling reaction was attempted, two different products were observed. (A) Draw a plausible catalytic cycle that explains the formation of the desired product. Label all mechanistic sticks. [Pd] can be used as the active catalyst. (B) Suggest how the undesired side-product may have formed. Hint: alkyl-Pd species are not particularly stable. Br ZnCl [Pd] catalyst desired product undesired side-product
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Please answer both parts of the question
![2. When the following Negishi cross-coupling reaction was attempted, two different products
were observed. (A) Draw a plausible catalytic cycle that explains the formation of the
desired product. Label all mechanistic sticks. [Pd] can be used as the active catalyst.
(B) Suggest how the undesired side-product may have formed. Hint: alkyl-Pd species
are not particularly stable.
Br
ZnCl
[Pd] catalyst
desired
product
undesired
side-product](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F6f01df11-7490-4fa9-9e51-6ea6d2a32aad%2F17102d53-7f08-47e5-ab16-8f3d2ddb6650%2F3megj6_processed.png&w=3840&q=75)
Transcribed Image Text:2. When the following Negishi cross-coupling reaction was attempted, two different products
were observed. (A) Draw a plausible catalytic cycle that explains the formation of the
desired product. Label all mechanistic sticks. [Pd] can be used as the active catalyst.
(B) Suggest how the undesired side-product may have formed. Hint: alkyl-Pd species
are not particularly stable.
Br
ZnCl
[Pd] catalyst
desired
product
undesired
side-product
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