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- Fluvastatin, a cholesterol-lowering drug, can be prepared by thefollowing three-step reaction sequence. Identify intermediates A and Band the final product, fluvastatin.Identify A, B, and C, intermediates in the synthesis of the five-membered ring called an α- methylene-γ-butyrolactone. This heterocyclic ring system is present in some antitumor agents.what is the major E1 product for the structure?
- Which compound is the major product of the reaction below? H2 Pd'charcoal (A) (B) (C) (D) Compound D Compound A Compound B O Compound C ncti 19 12 (4)Use the reaction given below to answer the following questions. A CH₂OH B H₂O+ C + CH3NH3* D a) What are the approximate pKas of compounds A and B? b) The reaction given above is irreversible. Give a detailed explanation of the reaction and reaction mechanism. Your explanation should indicate your knowledge of the reactivity of carboxylic acid derivatives.Show the products from reaction of p-bromoaniline with the following reagents: (a) CH3I (excess) (b) HCl (c) HNO2, H2SO4 (d) CH3COCl (e) CH3MgBr (f) CH3CH2Cl, AlCl3 (g) Product of (c) with CuCl, HCl (h) Product of (d) with CH3CH2Cl, AlCl3
- Propose a plausible mechanism for the following transformation: 1) Excess MeMgBr 2) H₂O HOWhich is the major product of the reaction below? (1) Na EtO /EIOH (2) dil H*, H-O (A) (B) H2COO OCH3 (C) OCH3 (D) OCH3 Compound A Compound D Compound C Compound BWhich of the following will be the dominant product of the dehydration reaction shown? H;PO, H2O. A но (A) (B) (C) (D) Compound B Compound C OCompoundD OCompound A nintc)
