2. What chemical shift range (or value), integration, and spin coupling (a.k.a. multiplicity) would you expect for the hydrogens in bold of the following molecules? OH H H. OH H. CI- Br A E A B C E d (ppm) integration multiplicity

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**Question 2: Chemical Shift Prediction for NMR Spectroscopy**

**Objective:**

Determine the expected chemical shift range or value, integration, and spin coupling (also known as multiplicity) for the hydrogens in bold within the following molecules:

**Molecules:**

- **A:** (3-bromo-2-methylbutane) with a bold hydrogen at position 3.
- **B:** (4-methylpent-2-ene) with a bold hydrogen on the alkene.
- **C:** (propanoic acid) with a bold hydrogen on the alpha carbon.
- **D:** (2-methylpropan-2-ol) with a bold hydrogen on the hydroxyl group.
- **E:** (2-chlorophenol) with a bold hydrogen on the aromatic ring.
- **F:** (butane) with a bold hydrogen at position 2.

**Data Table:**

|       | A    | B    | C    | D    | E    | F    |
|-------|------|------|------|------|------|------|
| **δ (ppm)**       |      |      |      |      |      |      |
| **Integration**   |      |      |      |      |      |      |
| **Multiplicity**  |      |      |      |      |      |      |

**Instructions:**

- **δ (ppm):** Predict the part per million (ppm) value where the hydrogen would resonate in an NMR spectrum.
- **Integration:** Predict how many hydrogens are represented by the signal.
- **Multiplicity:** Identify the splitting pattern (singlet, doublet, triplet, quartet, etc.).

Note: Provide detailed explanations for your predictions based on the surrounding chemical environment and molecular structure.
Transcribed Image Text:**Question 2: Chemical Shift Prediction for NMR Spectroscopy** **Objective:** Determine the expected chemical shift range or value, integration, and spin coupling (also known as multiplicity) for the hydrogens in bold within the following molecules: **Molecules:** - **A:** (3-bromo-2-methylbutane) with a bold hydrogen at position 3. - **B:** (4-methylpent-2-ene) with a bold hydrogen on the alkene. - **C:** (propanoic acid) with a bold hydrogen on the alpha carbon. - **D:** (2-methylpropan-2-ol) with a bold hydrogen on the hydroxyl group. - **E:** (2-chlorophenol) with a bold hydrogen on the aromatic ring. - **F:** (butane) with a bold hydrogen at position 2. **Data Table:** | | A | B | C | D | E | F | |-------|------|------|------|------|------|------| | **δ (ppm)** | | | | | | | | **Integration** | | | | | | | | **Multiplicity** | | | | | | | **Instructions:** - **δ (ppm):** Predict the part per million (ppm) value where the hydrogen would resonate in an NMR spectrum. - **Integration:** Predict how many hydrogens are represented by the signal. - **Multiplicity:** Identify the splitting pattern (singlet, doublet, triplet, quartet, etc.). Note: Provide detailed explanations for your predictions based on the surrounding chemical environment and molecular structure.
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