2. The following figure demonstrate the up-and-down experimental design. Discuss the trend Dose (mg kg- of body weight) 1.75 5.5 17.5 55.0 175.0 1st Grebe Bird response: O = Alive 2nd Grebe X= Dead 3rd Grebe X 4th Grebe 5th Grebe

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2. The following figure demonstrate the up-and-down experimental design. Discuss the trend
Dose (mg kg- of body weight)
1.75
5.5
17.5
55.0
175.0
1st Grebe
Bird response:
O = Alive
X= Dead
2nd Grebe
3rd Grebe
4th Grebe
5th Grebe
6th Grebe
7th Grebe
Proportion dead 0/3
3/3
1/1
Median lethal dose = 29.6 mg kg-1
Approximate 95% Confidence interval = 17.5 to 55.0 mg kg-l
Transcribed Image Text:2. The following figure demonstrate the up-and-down experimental design. Discuss the trend Dose (mg kg- of body weight) 1.75 5.5 17.5 55.0 175.0 1st Grebe Bird response: O = Alive X= Dead 2nd Grebe 3rd Grebe 4th Grebe 5th Grebe 6th Grebe 7th Grebe Proportion dead 0/3 3/3 1/1 Median lethal dose = 29.6 mg kg-1 Approximate 95% Confidence interval = 17.5 to 55.0 mg kg-l
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