2. The electron transfer potential of NADH and FADH2, relative to O2, drives oxidative phosphorylation and ATP synthesis. Oxidation of NADH occurs by the following reaction (1) : (1) 0.5 02 + NADH + H* H20 + NAD* The reaction above can be expressed in terms of the following half reactions: (2) 0.5 O2 + 2 H* + 2 e > H20 (3) NAD* + 2 H* + 2 e → NADH E. E, = -0.32 V = +0.82 V а. Calculate AE'0 and AGO for the oxidation of NADH (Reaction 1). b. What is AG'" for the synthesis of ATP from ADP? С. Using your results from Parts (a) and (b), explain how the electron transfer potential of NADH drives ATP synthesis.

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2. The electron transfer potential of NADH and FADH2, relative to O2, drives oxidative
phosphorylation and ATP synthesis. Oxidation of NADH occurs by the following reaction (1) :
(1)
0.5 02 + NADH + H* H20 + NAD*
The reaction above can be expressed in terms of the following half reactions:
(2) 0.5 O2 + 2 H* + 2 e > H20
(3) NAD+ + 2 H* + 2 e → NADH
E.
E,
= -0.32 V
= +0.82 V
Calculate AE'" and AGO for the oxidation of NADH (Reaction 1).
а.
b. What is AG'º for the synthesis of ATP from ADP?
c. Using your results from Parts (a) and (b), explain how the electron transfer potential of
NADH drives ATP synthesis.
Transcribed Image Text:2. The electron transfer potential of NADH and FADH2, relative to O2, drives oxidative phosphorylation and ATP synthesis. Oxidation of NADH occurs by the following reaction (1) : (1) 0.5 02 + NADH + H* H20 + NAD* The reaction above can be expressed in terms of the following half reactions: (2) 0.5 O2 + 2 H* + 2 e > H20 (3) NAD+ + 2 H* + 2 e → NADH E. E, = -0.32 V = +0.82 V Calculate AE'" and AGO for the oxidation of NADH (Reaction 1). а. b. What is AG'º for the synthesis of ATP from ADP? c. Using your results from Parts (a) and (b), explain how the electron transfer potential of NADH drives ATP synthesis.
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